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Gene Expression Data
Assay Details
Assay
Reference: J:198100 Andreeva V, et al., Rb1 mRNA expression in developing mouse teeth. Gene Expr Patterns. 2012 Mar-Apr;12(3-4):130-5
Assay type: RNA in situ
MGI Accession ID: MGI:5910414
Gene symbol: Rb1
Gene name: RB transcriptional corepressor 1
Probe: Rb1 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lens Present 1A
Specimen 1B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: vibrissa follicle Present 1B
Specimen 1C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: head bone Present Regionally restricted 1C Expression is in the prefrontal bone.
Specimen 2A: embryonic day 12.5 (more )
Note: Bud stage tooth.
Structure Level Pattern Image Note
TS20: jaw Trace Regionally restricted 2A Expression is barely detetcted in teeth.
Specimen 2D: embryonic day 14.5 (more )
Note: Cap stage tooth.
Structure Level Pattern Image Note
TS22: molar Trace 2D Expression is barely detetcted.
Specimen 3A: embryonic day 16.5 (more )
Note: Bell stage tooth. A1 and A2 are higher magnifications of the boxed areas in A1.
Structure Level Pattern Image Note
TS24: molar enamel organ Present Regionally restricted 3A , 3A1 , 3A2 Expression is in the inner enamel epithelium.
TS24: molar epithelium Present Regionally restricted 3A2 , 3A1 , 3A Expression is in the outer dental epithelium.
TS24: molar mesenchyme Present Regionally restricted 3A2 , 3A1 , 3A
TS24: dental sac Present 3A , 3A1 , 3A2
Specimen 4A: postnatal day 0 (more )
Note: A1 is a higher magnification of the boxed area in A.
Structure Level Pattern Image Note
TS27: molar enamel organ Strong Regionally restricted 4A , 4A1 Expression is in differentiated ameloblasts and weak expression in less differentiated pre-ameloblasts.
TS27: molar mesenchyme Present Regionally restricted 4A , 4A1 Expression is stronger in less differentiated odontoblasts, as compared to differentiated odontoblasts.
TS27: jaw Present Regionally restricted 4A , 4A1 Expression is in osteoblasts in the alveolar bone that surrounds the tooth.
TS27: molar dental pulp Weak 4A1 , 4A
Specimen 5A: postnatal day 0 (more )
Note: A1 and A2 are higher magnifications of the boxed areas in A1.
Structure Level Pattern Image Note
TS27: incisor epithelium Present 5A1 , 5A , 5A2
TS27: incisor mesenchyme Present 5A1 , 5A , 5A2
TS27: incisor enamel organ Strong Regionally restricted 5A1 , 5A2 , 5A Expression is stronger in differentiated ameloblasts as compared to less differentiated pre-ameloblasts.
TS27: incisor Strong Regionally restricted 5A2 , 5A1 , 5A Expression is higher in the labial side undifferentiated odontoblasts, as compared to terminally differentiated lingual side odontoblasts.
TS27: jaw Present Regionally restricted 5A1 , 5A2 , 5A Expression is in the alveolar bone surrounding the tooth.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory