Tg(Actb-EGFP,-Diaph1)#Cpm
Transgene Detail
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| Symbol: |
Tg(Actb-EGFP,-Diaph1)#Cpm |
| Name: |
transgene insertion, Christopher P Mack |
| MGI ID: |
MGI:5910313 |
| Synonyms: |
DNmDia |
| Transgene: |
Tg(Actb-EGFP,-Diaph1)#Cpm Location: unknown
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| Alliance: |
Tg(Actb-EGFP,-Diaph1)#Cpm page
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| Transgene Type: |
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Transgenic (Conditional ready, Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Tg(Actb-EGFP,-Diaph1)#Cpm expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Diaph1 (MGI:1194490) |
dominant negative construct lacking N-terminal half and more |
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Mutation details: A vector containing the mouse beta actin promoter, a loxP site flanked EGFP gene and STOP cassette, and the cDNA for the dominant negative mutant construct of the mouse gene (F1FHdelta1) with a FLAG tag, was used to generate this allele. This creates a conditional-ready allele that will only express the mouse gene after the EGFP-STOP cassette is removed through cre-mediated recombination. No line information was given (denoted by the pound sign #).
(J:242113)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:242113 Weise-Cross L, et al., Inhibition of Diaphanous Formin Signaling In Vivo Impairs Cardiovascular Development and Alters Smooth Muscle Cell Phenotype. Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):2374-83 |
| All: |
1 reference(s) |
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Analysis Tools
