Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Mslntm1.1(cre/ERT2)Ilw
Name:	mesothelin; targeted mutation 1.1, Irving L Weissman
MGI ID:	MGI:5910114
Synonyms:	MslnCLN, MslnnLacZ-ER-Cre
Gene:	Msln  Location: Chr17:25967587-25973352 bp, - strand  Genetic Position: Chr17, 12.85 cM, cytoband A3.3
Alliance:	Mslntm1.1(cre/ERT2)Ilw page

Germline Transmission:	Earliest citation of germline transmission: J:195251
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Null/knockout, Recombinase, Reporter) Inducer:    tamoxifen Mutations:    Insertion, Intragenic deletion   Mslntm1.1(cre/ERT2)Ilw expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Msln (MGI:1888992)   Mutation details: The ATG start codon of Msln gene was replaced by the CreERT2-IRES-lacZ-polyA signal and FRT-flanked PGKneo cassetter in exon 1. CThe neo cassette was laater removed by crossing with Flpe-expressing mice. (J:195251)

Activity:	Tissue activity of this recombinase allele
Driver:	Msln (mouse) Summary of all recombinase alleles driven by Msln. Alliance mouse Msln gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msln Mutation:	36 strains or lines available

Original:	J:195251 Rinkevich Y, et al., Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature. Nat Cell Biol. 2012 Dec;14(12):1251-60
All:	3 reference(s)