Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Mfsd2aem1(cre/ERT2)Bzsh
Name:	MFSD2 lysolipid transporter A, lysophospholipid; endonuclease-mediated mutation 1, Bin Zhou
MGI ID:	MGI:5909986
Synonyms:	Mfsd2a-CreER
Gene:	Mfsd2a  Location: Chr4:122840643-122854981 bp, - strand  Genetic Position: Chr4, 57.34 cM, cytoband D1
Alliance:	Mfsd2aem1(cre/ERT2)Bzsh page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Mfsd2aem1(cre/ERT2)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Mfsd2a (MGI:1923824)   Mutation details: The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. A complementary DNA encoding Cre recombinase fused with a mutant form of the ESR hormone-binding domain (CreERT2) was inserted in frame with the translational start codon of the Mfsd2a gene. (J:242859)

Activity:	Tissue activity of this recombinase allele
Driver:	Mfsd2a (mouse) Summary of all recombinase alleles driven by Mfsd2a. Comparative matrix view of recombinase activities Alliance mouse Mfsd2a gene page

In Mice Carrying this Mutation:

8 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mfsd2a Mutation:	36 strains or lines available

Original:	J:242859 Pu W, et al., Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration. Nat Commun. 2016 Nov 18;7:13369
All:	6 reference(s)