Tg(TcraLLO118,TcrbLLO118)#Pmal
Transgene Detail
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| Symbol: |
Tg(TcraLLO118,TcrbLLO118)#Pmal |
| Name: |
transgene insertion, Paul M Allen |
| MGI ID: |
MGI:5909865 |
| Synonyms: |
LL0118, LLO118 |
| Transgene: |
Tg(TcraLLO118,TcrbLLO118)#Pmal Location: unknown
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| Alliance: |
Tg(TcraLLO118,TcrbLLO118)#Pmal page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene contains pre-arranged Tcr loci from a CD4+ cell line LLO118 (Valpha2 Vbeta2), which recognizes the immunodominant Listeria monocytogenes epitope listeriolysin residues 190-205. Cell line LL056 differs from LLO118 by 15 amino acids in the complementaruty determing regions (CDR). The leader region (from 2B4 TCR) and constant region (C1) were added to the transgene. The pound symbol is used when no line is specified and/or lines are pooled.
(J:185522)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:185522 Weber KS, et al., Distinct CD4+ helper T cells involved in primary and secondary responses to infection. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9511-6 |
| All: |
6 reference(s) |
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Analysis Tools
