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Tg(Tcra,Tcrb)gagOhln
Transgene Detail
Summary
Symbol: Tg(Tcra,Tcrb)gagOhln
Name: transgene insertion gag, Claes Ohlen
MGI ID: MGI:5909422
Synonyms: TCRxgag
Transgene: Tg(Tcra,Tcrb)gagOhln  Location: unknown  
Alliance: Tg(Tcra,Tcrb)gagOhln page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene contains pre-arranged Tcr loci from CD8+ cytotoxic clones of mice primed with irradiated FBL tumor that recognizes the Friend murine leukemia virus leader sequence of the gag protein epitope (85 CCLCLTVFL 93). Gag was used to represent the line as no clone line was identified. (J:133063)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:133063 Ohlen C, et al., CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function. J Exp Med. 2002 Jun 3;195(11):1407-18
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory