Tg(Tcra7-3-7,Tcrb7-3-7)23-3Habu Transgene Detail MGI Mouse (MGI:5909420)

Tg(Tcra7-3-7,Tcrb7-3-7)23-3Habu
Transgene Detail

Summary

Symbol:	Tg(Tcra7-3-7,Tcrb7-3-7)23-3Habu
Name:	transgene insertion 23-3, Sonoko Habu
MGI ID:	MGI:5909420
Synonyms:	OVA-23-3
Transgene:	Tg(Tcra7-3-7,Tcrb7-3-7)23-3Habu Location: unknown
Alliance:	Tg(Tcra7-3-7,Tcrb7-3-7)23-3Habu page

Transgene
origin

Strain of Origin:

Not Specified

Transgene
description

Transgene Type:		Transgenic (Inserted expressed sequence)
Mutation:		Insertion
		Mutation details: The transgene contrains pre-arranged Tcr loci from ovalbumin-reactive T cell clone 7-3-7 (ValphaHDS58-JalphaBDFLII Vbeta15-Dbeta1-Jbeta2.2), which recognizes ovalbumin residues 323-339. Calpha and enhancer sequence were inserted. The first exon and upstream fragment of Vbeta5.2 was inserted at the 5' end of Vbeta15. Lines OVA-8-3 and OVA-23-3 were generated. (J:19310)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Transgenes were microinjected into fertilized eggs of (C57BL/6 x DBA)F1 x BALB/c or (C57BL/6 x DBA)F1 x (C57BL/6 x DBA)F1.

References

Original:	J:19310 Sato T, et al., Naive T cells can mediate delayed-type hypersensitivity response in T cell receptor transgenic mice. Eur J Immunol. 1994 Jul;24(7):1512-6
All:	3 reference(s)

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