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Tg(TcraA23,TcrbA23)#Etms
Transgene Detail
Summary
Symbol: Tg(TcraA23,TcrbA23)#Etms
Name: transgene insertion, Ethan M Shevach
MGI ID: MGI:5909331
Synonyms: A23 Tg
Transgene: Tg(TcraA23,TcrbA23)#Etms  Location: unknown  
Alliance: Tg(TcraA23,TcrbA23)#Etms page
Transgene
origin
Strain of Origin:  (C57BL/6 x BALB/c)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene contains pre-arranged Tcr loci from the TxA23 clone (AVA2S6 AJ32 BV2S1 BJ1.1) derived from the gastric lymph nodes of a thymectomized on day 3 of life (d3Tx) mouse. The clone recognizes the minimal antigenic epitope of Atp4a (residues 633-641). The pound symbol (#) is used when no line is specified and/or ines are pooled. (J:70405)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:70405 McHugh RS, et al., A T cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity. Eur J Immunol. 2001 Jul;31(7):2094-103
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory