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Tg(Tcra1E4.C1,Tcrb1E4.C1)#Fald
Transgene Detail
Summary
Symbol: Tg(Tcra1E4.C1,Tcrb1E4.C1)#Fald
Name: transgene insertion, Frank Alderuccio
MGI ID: MGI:5909321
Synonyms: 1E4-TCR
Transgene: Tg(Tcra1E4.C1,Tcrb1E4.C1)#Fald  Location: unknown  
Alliance: Tg(Tcra1E4.C1,Tcrb1E4.C1)#Fald page
Transgene
origin
Strain of Origin:  (BALB/c x C57BL/6) X BALB/c
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene contains prearranged Tcr loci from CD4 T cell hybridoma 1E4.C1 (Valpha9Jalpha21 and Vbeta8.3Dbeta1Jbeta2.1), which recognizes the dominant gastritogenic epitope Atp4b residues 253-277. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:243631)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:243631 Alderuccio F, et al., Tolerance and autoimmunity to a gastritogenic peptide in TCR transgenic mice. Int Immunol. 2000 Mar;12(3):343-52
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory