Tg(TCRAMS2-3C8,TCRBMS2-3C8)#Kito
Transgene Detail
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| Symbol: |
Tg(TCRAMS2-3C8,TCRBMS2-3C8)#Kito |
| Name: |
transgene insertion, Kouichi Ito |
| MGI ID: |
MGI:5909274 |
| Synonyms: |
MS2-3C8 |
| Transgene: |
Tg(TCRAMS2-3C8,TCRBMS2-3C8)#Kito Location: unknown
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| Alliance: |
Tg(TCRAMS2-3C8,TCRBMS2-3C8)#Kito page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene contains rearranged MS2-3C8 TCR Valpha (AV4S1AJ32) and Vbeta (BV2S1BJ1S6) chains from the T cell clone MS2-3C8 isolated from the peripheral blood of a patient with relapsing/remitting multiple sclerosis, which recognizes the human MBP 111-129 epitope. Lines B6 and G2 were generated. The pound symbol is used when no line is specified and/or lines are pooled.
(J:91285)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:140763 Kawamura K, et al., Different development of myelin basic protein agonist- and antagonist-specific human TCR transgenic T cells in the thymus and periphery. J Immunol. 2008 Oct 15;181(8):5462-72 |
| All: |
2 reference(s) |
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Analysis Tools
