Tg(TcraBW5147,TcrbBW5147)G206Mcd
Transgene Detail
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| Symbol: |
Tg(TcraBW5147,TcrbBW5147)G206Mcd |
| Name: |
transgene insertion G206, Hugh O McDevitt |
| MGI ID: |
MGI:5909272 |
| Synonyms: |
G206, Valpha5-Jalpha45, Vbeta8.1-Jbeta2.4 |
| Transgene: |
Tg(TcraBW5147,TcrbBW5147)G206Mcd Location: unknown
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| Alliance: |
Tg(TcraBW5147,TcrbBW5147)G206Mcd page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene contains a pre-arranged Tcr locus from the hybridoma cell line BW5147 (Valpha5-Jalpha45, Vbeta8.1-Jbeta2.4), which recognizes the GAD2 p206 (TYEIAPVFVLLEYVT) epitope. Three lines were generated with line G206 selected as the representative line.
(J:93437)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:93437 Kim SK, et al., Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells. Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14204-9 |
| All: |
1 reference(s) |
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