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Gene Expression Data
Assay Details
Assay
Reference: J:232556 Bao J, et al., UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts. PLoS Genet. 2016 May;12(5):e1005863
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5908580
Gene symbol: Upf2
Gene name: UPF2 regulator of nonsense transcripts homolog (yeast)
Antibody: anti-hUPF2
Results
Specimen 1B: postnatal adult (more )
Note: Double labeled: green - Upf2; blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatid Present Regionally restricted 1B a-UPF2 Abundant expression in cytoplasm of spermatocytes and round spermatids. Highest expression confined to an intensive "dot-like" structure resembling the chromatoid body (CB) in round spermatids.
Specimen 1C: postnatal adult (more )
Note: Triple labeled: red - Upf2; green - Mael (assay MGI:5908581); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatid Present Regionally restricted 1C UPF2 , 1C MERGE Authors report consistent co-localization with chromatoid body (CB) marker MAEL in most round spermatids.
Specimen 1D: postnatal adult (more )
Note: Triple labeled: green - Upf2; red - Ddx25 (assay MGI:5908582) blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatid Present Regionally restricted 1D UPF2 , 1D MERGE Authors report consistent co-localization with chromatoid body (CB) marker DDX25 in most round spermatids at both stages VIII and I.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory