Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gng8tm1.1(cre)Irod
Name:	guanine nucleotide binding protein (G protein), gamma 8; targeted mutation 1.1, Ivan Rodriguez
MGI ID:	MGI:5908376
Synonyms:	Gng8cre
Gene:	Gng8  Location: Chr7:16625711-16629361 bp, + strand  Genetic Position: Chr7, 9.15 cM
Alliance:	Gng8tm1.1(cre)Irod page

Germline Transmission:	Earliest citation of germline transmission: J:237342
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Gng8tm1.1(cre)Irod expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gng8 (MGI:109163)   Mutation details: An IRES-cre with an FRT-flanked neo cassette was inserted into downstream of the coding region of Gng8 gene in ES cell by homologous recombination. To remove the neo cassette, mice were bred to Flp deleter mice. (J:237342)

Activity:	Tissue activity of this recombinase allele
Driver:	Gng8 (mouse) Summary of all recombinase alleles driven by Gng8. Comparative matrix view of recombinase activities Alliance mouse Gng8 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gng8 Mutation:	10 strains or lines available

Original:	J:237342 Assens A, et al., Alteration of Nrp1 signaling at different stages of olfactory neuron maturation promotes glomerular shifts along distinct axes in the olfactory bulb. Development. 2016 Oct 15;143(20):3817-3825
All:	1 reference(s)