Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gnrhrtm1.1(cre/ERT2)Djb
Name:	gonadotropin releasing hormone receptor; targeted mutation 1.1, Daniel J Bernard
MGI ID:	MGI:5908151
Synonyms:	iGRIC
Gene:	Gnrhr  Location: Chr5:86328613-86345760 bp, - strand  Genetic Position: Chr5, 43.56 cM
Alliance:	Gnrhrtm1.1(cre/ERT2)Djb page

Germline Transmission:	Earliest citation of germline transmission: J:262146
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Gnrhrtm1.1(cre/ERT2)Djb expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gnrhr (MGI:95790)     An IRES-cre/ERT2 and frt-flanked neo cassette were inserted downstream of exon 3. (J:262146)

Activity:	Tissue activity of this recombinase allele
Driver:	Gnrhr (mouse) Summary of all recombinase alleles driven by Gnrhr. Alliance mouse Gnrhr gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gnrhr Mutation:	20 strains or lines available

Original:	J:262146 Li Y, et al., Conditional deletion of FOXL2 and SMAD4 in gonadotropes of adult mice causes isolated FSH deficiency. Endocrinology. 2018 May 23;
All:	1 reference(s)