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Gene Expression Data
Assay Details
Assay
Reference: J:98688 Tang LS, et al., Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear. Gene Expr Patterns. 2005 Jun;5(5):587-92
Assay type: RNA in situ
MGI Accession ID: MGI:5907892
Gene symbol: Nr2f2
Gene name: nuclear receptor subfamily 2, group F, member 2
Probe: Aporp1 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1E: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS14: otic placode epithelium Present Regionally restricted 1E Earliest expression at E8.75 (17 somites) in ventral-anterior domain of otic placode epithelium.
TS14: 1st branchial arch Present 1E
TS14: 2nd branchial arch Present 1E
Specimen 1F: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 1F Authors state expression in otic vesicle expanded posteriorly.
TS15: 1st branchial arch Present 1F
TS15: 2nd branchial arch Present 1F
Specimen 1G: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS15: otocyst Strong Regionally restricted 1G In 26 somite embryos, strong expression in ventral-posterior domain of otic vesicle.
Specimen E13.5 not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cochlear duct epithelium Present Regionally restricted Expression only in distal tip of elongating cochlear epithelium.
Specimen 2K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Present Uniform 2K Homogeneous pattern of expresion in epithelium.
Specimen 2L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: greater epithelial ridge Present 2L No demarcation between greater epithelial ridge and lesser epithelial ridge in apical coil.
TS23: lesser epithelial ridge Present 2L No demarcation between greater epithelial ridge and lesser epithelial ridge in apical coil.
Specimen 2M: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Weak Regionally restricted 2M Authors report significant reduction of expression at middle to basal coils.
Specimen 2N: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Trace Regionally restricted 2N Almost undetectable levels in middle to basal coils.
Specimen 2O: embryonic day 15.5; Nr2f1tm1Mjts/Nr2f1tm1Mjts (more )
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Present Regionally restricted 2O Similar levels of expression as that seen in wild type ears.
Specimen postnatal not shown: postnatal (more )
Structure Level Pattern Image Note
TS28: organ of Corti Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory