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Fcgr3tm2Jsv
Targeted Allele Detail
Summary
Symbol: Fcgr3tm2Jsv
Name: Fc receptor, IgG, low affinity III; targeted mutation 2, J Sjef Verbeek
MGI ID: MGI:5907362
Gene: Fcgr3  Location: Chr1:170878743-170892504 bp, - strand  Genetic Position: Chr1, 78.8 cM
Alliance: Fcgr3tm2Jsv page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:264675
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 4, encoding extracellular domain 2 (EC2). An FRT-flanked hygromycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. (J:264675)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fcgr3 Mutation:  29 strains or lines available
References
Original:  J:264675 Fransen MF, et al., A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory