Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Myh6/tetO-Ddit4l)1Sdas
Name:	transgene insertion 1, Saumya Das
MGI ID:	MGI:5906021
Synonyms:	DDiT4L, HA-DDiT4L
Transgene:	Tg(Myh6/tetO-Ddit4l)1Sdas  Location: unknown
Alliance:	Tg(Myh6/tetO-Ddit4l)1Sdas page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Epitope tag, Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(Myh6/tetO-Ddit4l)1Sdas expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Ddit4l (MGI:1920534)   Mutation details: The transgenic construct contains the mouse DNA-damage-inducible transcript 4-like (Ddit4l) gene, tagged with human influenza hemagglutinin, under the control of the tetO/Myh6, tet-operator (tetracycline-responsive element) and mouse myosin, heavy polypeptide 6, cardiac muscle, alpha (alpha-MHC) fusion promoter. (J:242621)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:242621 Simonson B, et al., DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress. Sci Signal. 2017 Feb 28;10(468)
All:	1 reference(s)