|
Results
|
Specimen
1 H:
postnatal day 7
(more  )
Note: Quantification of confocal analyses are shown in Figure 2A.
Specimen
1 H:
(close  )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 7
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Quantification of confocal analyses are shown in Figure 2A.
|
Specimen
1 BO:
postnatal day 7
(more )
Note: Quantification of confocal analyses are shown in Figure 2A.
Specimen
1 BO:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 7
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Quantification of confocal analyses are shown in Figure 2A.
|
Specimen
S1 WT:
postnatal day 7
(more )
Specimen
S1 WT:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 7
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
S1 SV2A-/-;SV2B-/-:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Sv2atm1Sud/Sv2atm1Sud
Sv2btm1Sud/Sv2btm1Sud
|
|
Age:
|
postnatal day 7
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
S2 WT:
postnatal
(more )
Specimen
S2 WT:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
S2 SV2A+/-:
postnatal; Sv2atm1Sud/Sv2a +
(more )
Specimen
S2 SV2A+/-:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Sv2atm1Sud/Sv2a+
|
|
Age:
|
postnatal
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
S2 SV2A-/-:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Sv2atm1Sud/Sv2atm1Sud
|
|
Age:
|
postnatal
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 E12:
embryonic day 12.0
(more )
Specimen
Table 1 E12:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
embryonic day 12.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 E14:
embryonic day 14.0
(more )
Specimen
Table 1 E14:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
embryonic day 14.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 E16:
embryonic day 16.0
(more )
Specimen
Table 1 E16:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
embryonic day 16.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: main olfactory bulb |
Very strong |
Regionally restricted |
|
Expression is in the glomerular region and is weak in the fascicular region.
|
| TS24: hippocampus |
Very strong |
Regionally restricted |
|
Expression is in the CA4 region, weak in the CA1 region, and is absent in the dentate gyrus.
|
| TS24: telencephalon septum |
Very strong |
Regionally restricted |
|
Expression is in the stria terminalis nucleus.
|
| TS24: amygdala |
Very strong |
|
|
|
| TS24: cochlear nucleus |
Very strong |
|
|
|
| TS24: geniculate thalamic group |
Very strong |
|
|
|
| TS24: habenula |
Very strong |
|
|
|
| TS24: pretectum |
Very strong |
|
|
|
| TS24: midbrain |
Very strong |
Regionally restricted |
|
Expression is in the substantia nigra, per-aqueductal grey matter, common oculomotor nucleus, and red nucleus and is moderate in the ventral tegmental area.
|
| TS24: ventral striatum |
Very strong |
Regionally restricted |
|
Expression is in the nucleus accumbens.
|
| TS24: telencephalon |
Very strong |
Regionally restricted |
|
Expression is in the septal lateral nucleus and septo-fimbrial nucleus.
|
| TS24: pallidum |
Very strong |
Regionally restricted |
|
Expression is in the magno-cellular nucleus.
|
| TS24: pons |
Very strong |
Regionally restricted |
|
Expression is in the facial nucleus, superior olivary nucleus, and moderate in the trigeminal V motor nucleus.
|
| TS24: medulla oblongata |
Very strong |
Regionally restricted |
|
Expression is in the cuneus nucleus, solitary tract nuclleus, nucleus ambiguus, dorsal motor nucleus of vagus nerve, hypoglossal nucleus, and moderate in inferior olivary nucleus.
|
| TS24: caudate-putamen |
Moderate |
|
|
|
| TS24: cerebral cortex |
Moderate |
|
|
|
| TS24: superior colliculus |
Moderate |
|
|
|
| TS24: thalamus |
Moderate |
Regionally restricted |
|
Expression is in the anterior thalamus.
|
| TS24: hypothalamus |
Moderate |
Regionally restricted |
|
Expression is in the periventricular region, the preoptic nucleus, arcuetes nucleus, paraventricular nucleus, mammillary bodies, the paraventricular region, and supra-chiasmatic nucleus, and is absent in the medial hypothalamus.
|
| TS24: brainstem nucleus |
Moderate |
Regionally restricted |
|
Expression is in the raphe nucleus and vestibular nucleus.
|
| TS24: cerebellum |
Absent |
|
|
|
| TS24: cerebral hemisphere white matter |
Absent |
|
|
|
| TS24: dentate nucleus |
Absent |
|
|
|
| TS24: fastigial nucleus |
Absent |
|
|
|
| TS24: inferior colliculus |
Absent |
|
|
|
Specimen
Table 1 E18:
embryonic day 18.0
(more )
Specimen
Table 1 E18:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
embryonic day 18.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: main olfactory bulb |
Very strong |
Regionally restricted |
|
Expression is in the glomerular region and is moderate in the fascicular region.
|
| TS26: amygdala |
Very strong |
|
|
|
| TS26: cerebellum Purkinje cell layer |
Very strong |
|
|
|
| TS26: cochlear nucleus |
Very strong |
|
|
|
| TS26: facial nucleus |
Very strong |
|
|
|
| TS26: fastigial nucleus |
Very strong |
|
|
|
| TS26: hypoglossal nucleus |
Very strong |
|
|
|
| TS26: inferior colliculus |
Very strong |
|
|
|
| TS26: inferior olivary nucleus |
Very strong |
|
|
|
| TS26: periaqueductal grey |
Very strong |
|
|
|
| TS26: pretectum |
Very strong |
|
|
|
| TS26: substantia nigra |
Very strong |
|
|
|
| TS26: ventral tegmental area |
Very strong |
|
|
|
| TS26: pallidum |
Very strong |
Regionally restricted |
|
Expression is in the magno-cellular nucleus.
|
| TS26: midbrain |
Very strong |
Regionally restricted |
|
Expression is in the common oculomotor nucleus and red nucleus.
|
| TS26: brainstem nucleus |
Very strong |
Regionally restricted |
|
Expression is in the raphe nucleus and vestibular nucleus.
|
| TS26: pons |
Very strong |
Regionally restricted |
|
Expression is in the superior olivary nucleus, and moderate in the trigeminal V motor nucleus.
|
| TS26: medulla oblongata |
Very strong |
Regionally restricted |
|
Expression is in the facial nucleus, superior olivary nucleus, cuneus nucleus, solitary tract nucleus, nucleus ambiguus, dorsal motor nucleus of vagus nerve, hypoglossal nucleus, and moderate in inferior olivary nucleus and the trigeminal V motor nucleus.
|
| TS26: accumbens nucleus |
Moderate |
|
|
|
| TS26: caudate-putamen |
Moderate |
|
|
|
| TS26: cerebral cortex |
Moderate |
|
|
|
| TS26: dentate nucleus |
Moderate |
|
|
|
| TS26: habenula |
Moderate |
|
|
|
| TS26: hippocampus CA4 |
Moderate |
|
|
|
| TS26: superior colliculus |
Moderate |
|
|
|
| TS26: suprachiasmatic nucleus |
Moderate |
|
|
|
| TS26: ventral striatum |
Moderate |
|
|
|
| TS26: telencephalon septum |
Moderate |
Regionally restricted |
|
Expression is in the stria terminalis nucleus.
|
| TS26: thalamus |
Moderate |
Regionally restricted |
|
Expression is in the anterior-, ventral-, lateral-, and medio-dorsal thalamus.
|
| TS26: hypothalamus |
Moderate |
Regionally restricted |
|
Expression is in the periventricular region, the preoptic nucleus, arcuetes nucleus, paraventricular nucleus, mammillary bodies, the paraventricular region, and is absent in the medial hypothalamus.
|
| TS26: telencephalon |
Moderate |
Regionally restricted |
|
Expression is in the septal lateral nucleus and septo-fimbrial nucleus.
|
| TS26: geniculate thalamic group |
Weak |
|
|
|
| TS26: hippocampus CA1 |
Weak |
|
|
|
| TS26: cerebral hemisphere white matter |
Absent |
|
|
|
| TS26: dentate gyrus |
Absent |
|
|
|
| TS26: intralaminar thalamic group |
Absent |
|
|
|
Specimen
Table 1 P0:
postnatal day 0
(more )
Specimen
Table 1 P0:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P1:
postnatal day 1
(more )
Specimen
Table 1 P1:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P6:
postnatal day 6
(more )
Specimen
Table 1 P6:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P7:
postnatal day 7
(more )
Specimen
Table 1 P7:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 7
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P8:
postnatal day 8
(more )
Specimen
Table 1 P8:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 8
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P9:
postnatal day 9
(more )
Specimen
Table 1 P9:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 9
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P10:
postnatal day 10
(more )
Specimen
Table 1 P10:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 10
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P15:
postnatal day 15
(more )
Specimen
Table 1 P15:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 >/=30:
postnatal day 30
(more )
Specimen
Table 1 >/=30:
(close )
|
Genetic Background:
|
BALB/c
|
|
Age:
|
postnatal day 30
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Analysis Tools