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Gene Expression Data
Assay Details
Assay
Reference: J:181634 Wallgard E, et al., Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development. Dev Dyn. 2012 Apr;241(4):770-86
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5904502
Gene symbol: Pald1
Gene name: phosphatase domain containing, paladin 1
Reporter: lacZ
Antibody: beta-gal antibody
Results
Specimen 6k: postnatal day 5; Pald1tm1Vlcg/Pald1+ (more )
Note: Double labeled: red - Pald1 reporter; green - isolectin B4.
Structure Level Pattern Image Note
TS28: central nervous system vascular element Present Regionally restricted 6k Expression in subset of vascular smooth muscle cells.
Specimen 6l: postnatal day 5; Pald1tm1Vlcg/Pald1+ (more )
Note: Double labeled: red - Pald1 reporter; green - alpha-SMA (Acta2; assay MGI:5904517).
Structure Level Pattern Image Note
TS28: central nervous system vascular element Present Regionally restricted 6l Expression in subset of vascular smooth muscle cells.
Specimen 7c: postnatal adult; Pald1tm1Vlcg/Pald1+ (more )
Note: Double labeled: red - Pald1 reporter; green - alpha-SMA (Acta2; assay MGI:5904517).
Structure Level Pattern Image Note
TS28: brain blood vessel Present Regionally restricted 7c Expression in vascular smooth muscle cells.
Specimen 7d: postnatal adult; Pald1tm1Vlcg/Pald1+ (more )
Note: Double labeled: red - Pald1 reporter; green - isolecting B4.
Structure Level Pattern Image Note
TS28: brain blood vessel Present Regionally restricted 7d Authors report expression in cells surrounding the endothelium.
Specimen 7h: postnatal adult; Pald1tm1Vlcg/Pald1+ (more )
Note: Double labeled: red - Pald1 reporter; green - isolectin B4.
Structure Level Pattern Image Note
TS28: brain blood vessel Present Regionally restricted 7h Occasional expression in endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory