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Gene Expression Data
Assay Details
Assay
Reference: J:241982 Woltering JM, et al., Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits. PLoS Biol. 2014 Jan;12(1):e1001773
Assay type: RNA in situ
MGI Accession ID: MGI:5904290
Gene symbol: Hoxa11
Gene name: homeobox A11
Probe: Hoxa11 probe7
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A Hoxa11: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forearm Present Regionally restricted 2A Hoxa11 Expression in distal zeugopod.
TS20: hand Absent 2A Hoxa11 No expression only in presumptive digits.
Specimen 2B WT fl: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forearm Present 2B Hoxa11 WT fl
TS20: hand Absent 2B Hoxa11 WT fl
Specimen 2B WT hl: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lower leg Present 2B Hoxa11 WT hl
TS20: foot Absent 2B Hoxa11 WT hl
Specimen 2B Hoxa13-/- fl: embryonic day 12.5; Hoxa13tm2Ipc/Hoxa13tm2Ipc (more )
Structure Level Pattern Image Note
TS20: forearm Present 2B Hoxa11 Hoxa13-/- fl Expression shifts distally.
TS20: hand Present Regionally restricted 2B Hoxa11 Hoxa13-/- fl Expression extends into proximal autopod.
Specimen 2B Hoxa13-/- hl: embryonic day 12.5; Hoxa13tm2Ipc/Hoxa13tm2Ipc (more )
Structure Level Pattern Image Note
TS20: lower leg Present 2B Hoxa11 Hoxa13-/- hl Expression shifts distally.
TS20: foot Present Regionally restricted 2B Hoxa11 Hoxa13-/- hl Expression extends into proximal autopod.
Specimen 2B Hoxa13-/- Hoxd13-/- fl: embryonic day 12.5; Hoxa13tm2Ipc/Hoxa13tm2Ipc, Hoxd13tm1Ddu/Hoxd13tm1Ddu (more )
Structure Level Pattern Image Note
TS20: forearm Present 2B Hoxa11 Hoxa13-/- Hoxd13-/- fl Expression spreads further distally.
TS20: hand Present Widespread 2B Hoxa11 Hoxa13-/- Hoxd13-/- fl Expression almost throughout the developing autopod.
Specimen 2B Hoxa13-/- Hoxd13-/- hl: embryonic day 12.5; Hoxa13tm2Ipc/Hoxa13tm2Ipc, Hoxd13tm1Ddu/Hoxd13tm1Ddu (more )
Structure Level Pattern Image Note
TS20: lower leg Present 2B Hoxa11 Hoxa13-/- Hoxd13-/- hl Expression spreads further distally.
TS20: foot Present Widespread 2B Hoxa11 Hoxa13-/- Hoxd13-/- hl Expression almost throughout the developing autopod.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory