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Gene Expression Data
Assay Details
Assay
Reference: J:206212 Leung KK, et al., Angiotensin II type 2 receptor regulates the development of pancreatic endocrine cells in mouse embryos. Dev Dyn. 2014 Mar;243(3):415-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5904279
Gene symbol: Ins1
Gene name: insulin I
Antibody: anti-insulin
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 2 e12.5 top: embryonic day 12.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS20: pancreas parenchyma Present Single cells 2_top e12.5 Expression is in beta cell progenitors.
Specimen 2 e15.5 top: embryonic day 15.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 2_top e15.5 Expression is in beta cells.
Specimen 2 e17.5 top: embryonic day 17.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS25: islets of Langerhans Present Regionally restricted 2_top e17.5 Expression is in clusters of beta cells.
Specimen 2 neonate top: postnatal newborn (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present Regionally restricted 2_top neonate Expression is in beta cells.
Specimen 2 e12.5 bottom: embryonic day 12.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS20: pancreas parenchyma Present Single cells 2_bottom e12.5 , 2_bottom e12.5 insert Expression is in beta cell progenitors.
Specimen 2 e15.5: embryonic day 15.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 2_bottom e15.5 insert , 2_bottom e15.5 Expression is in beta cells.
Specimen 2 e17.5: embryonic day 17.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS25: islets of Langerhans Present Regionally restricted 2_bottom e17.5 insert , 2_bottom e17.5 Expression is in clusters of beta cells.
Specimen 2 neonate: postnatal newborn (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present Regionally restricted 2_bottom neonate insert , 2_bottom neonate Expression is in beta cells.
Specimen S2 islet top: postnatal adult (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present Regionally restricted S2_top left Expression is in beta cells.
Specimen S2 islet bottom: postnatal adult (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present Regionally restricted S2_bottom left Expression is in beta cells.
Specimen S2 kidney top: postnatal adult (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS28: metanephros Absent S2_top center
Specimen S2 kidney bottom: postnatal adult (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS28: metanephros Absent S2_bottom center
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory