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Gene Expression Data
Assay Details
Assay
Reference: J:16894 Yamagata T, et al., Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Brain Res Dev Brain Res. 1994 Feb 18;77(2):163-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5904053
Gene symbol: Rarb
Gene name: retinoic acid receptor, beta
Antibody: anti-RARbeta
Detection system: horseradish peroxidase
Results
Specimen 3a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3a Expression in ventral region of mantle layer and ependymal layer. No expression in dorsal region. No expression in alar plate.
TS17: neural tube floor plate Present 3a Expression in cells around floor plate.
Specimen 4b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord mantle layer Present Diffuse 4b Most prominent and diffuse expression in most young neurons in the mantle layer.
TS20: spinal cord ventricular layer Present Regionally restricted 4b Expression in some cells in ependymal layer.
Specimen 16.5 day spinal cord not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Weak Regionally restricted Weak expression in ventral region.
Specimen 5b: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: spinal cord Weak Regionally restricted 5b Expression in small number of cells in ventral region. No expression in dorsal region.
Specimen 5f: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: spinal cord Weak Regionally restricted 5f Figure shows expression in alar plate.
Specimen 5j: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: spinal cord Weak Regionally restricted 5j Figure shows expression in basal plate.
Specimen 6 ED 10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Trace 6_RAR-beta ED 10.5 Expression gradually and diffusely increased thereafter.
Specimen 6 ED 11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present 6_RAR-beta ED 11.5
Specimen 6 ED 12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 6_RAR-beta ED 12.5
Specimen 6 ED 14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Present 6_RAR-beta ED 14.5
Specimen 6 ED 16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Weak 6_RAR-beta ED 16.5 Expression started to decrease at 16.5 days.
Specimen 6 NEWBORN: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: spinal cord Ambiguous 6_RAR-beta NEWBORN
Specimen 7a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain ventricular layer Present 7a Expression in some cells in ependymal layer.
TS20: midbrain mantle layer Present 7a Expression in many cells in mantle layer.
Specimen 7c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain ventricular layer Present 7c Expression in some cells in ependymal layer.
TS20: midbrain mantle layer Present 7c Expression in many cells in mantle layer.
Specimen 8b: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hippocampus Weak 8b Expression in small number of cells in primordium of hippocampus.
Specimen 8e: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Strong Regionally restricted 8e Increased intensity of expression and number of expressing cells in pyramidal cell layer.
Specimen 8h: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: hippocampus Weak 8h Decreased expression in newborn.
Specimen 9b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Absent 9b No expression in telencephalon (neocortex, paleocortex).
Specimen 9e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral hemisphere white matter Present Regionally restricted 9e Expression in surface of cingulum.
Specimen 9h: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: neocortex Absent 9h
Specimen 9k: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present Widespread 9k Increase in number of expressing cells. Expression over entire cerebral cortex (neocortex, paleocortex).
Specimen 9n: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Strong 9n Expression more intense in newborn cortex (neocortex, paleocortex).
TS27: cortical plate Present Widespread 9n Expression in most neurons in cortical plate.
Specimen ED 12.5 brain not shown: embryonic day 12.5 (more )
Note: Data presented in Table 1.
Structure Level Pattern Image Note
TS20: thalamus Absent
TS20: corpus striatum Ambiguous
Specimen ED 14.5 brain not shown: embryonic day 14.5 (more )
Note: Data presented in Table 1.
Structure Level Pattern Image Note
TS22: corpus striatum Ambiguous
TS22: thalamus Present
TS22: midbrain Strong
Specimen ED 16.5 brain not shown: embryonic day 16.5 (more )
Note: Data presented in Table 1.
Structure Level Pattern Image Note
TS24: corpus striatum Present
TS24: midbrain Strong
TS24: thalamus Strong
Specimen Newborn brain not shown: postnatal newborn (more )
Note: Data presented in Table 1.
Structure Level Pattern Image Note
TS27: thalamus Ambiguous
TS27: corpus striatum Present
TS27: midbrain Present
Specimen 10b: postnatal adult (more )
Structure Level Pattern Image Note
TS28: parietal cortex Present 10b
Specimen 10f: postnatal adult (more )
Structure Level Pattern Image Note
TS28: temporal lobe Strong 10f Authors report Rarb expressed more intensely than Rara and Rarg in temporal region.
Specimen 11b: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Absent 11b
Specimen 11f: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Regionally restricted 11f Expression in some but not all Purkinje cells.
TS28: cerebellum granule cell layer Present 11f
Specimen 11j: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hypothalamus Strong 11j Authors report greater intensity of expression of Rara compared with Rarb and Rarg.
Specimen 11n: postnatal adult (more )
Structure Level Pattern Image Note
TS28: 4th ventricle ependyma Trace 11n
TS28: 4th ventricle choroid plexus Ambiguous 11n
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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