About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:203003 Janke A, et al., A new look at cytoskeletal NOS-1 and beta-dystroglycan changes in developing muscle and brain in control and mdx dystrophic mice. Dev Dyn. 2013 Dec;242(12):1369-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5903856
Gene symbol: Dag1
Gene name: dystroglycan 1
Antibody: anti-bDG (NCL-43DAG)
Detection system: Secondary antibody coupled to DyLight 649
Results
Specimen 3A P10 control: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 3A bDG control P10 Expression is as a smooth continuous outline around the fibers.
Specimen 3A P10 mdx: postnatal day 10; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 3A bDG mdx P10 Expression is in uneven patches at the fiber membrane.
Specimen 3A P28 control: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 3A bDG control P28 Expression is at the fiber membrane.
Specimen 3A P28 mdx: postnatal day 28; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 3A bDG mdx P28 Expression is in uneven patches at the fiber membrane.
Specimen 3B P10 control: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 3B bDG control P10 Expression is at the fiber membrane.
Specimen 3B P10 mdx: postnatal day 10; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 3B bDG mdx P10 Expression is in uneven patches at the fiber membrane.
Specimen 3B P28 control: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 3B bDG control P28 Expression is at the fiber membrane.
Specimen 3B P28 mdx: postnatal day 28; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 3B bDG mdx P28 Expression is in uneven patches at the fiber membrane.
Specimen 3C P10 control: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: muscle tissue Present 3C bDG control P10 , 3C bDG control x100 Expression is at the fiber membrane.
Specimen 3C P28 control: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: muscle tissue Present 3C bDG control P28 Expression is at the fiber membrane.
Specimen 3C P28 mdx: postnatal day 28; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: muscle tissue Present 3C bDG mdx P28 Expression is in uneven patches at the fiber membrane.
Specimen 5B left: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Punctate 5B left panel There is punctate staining around Purkinje neuron somata.
TS28: blood vessel smooth muscle Very strong Regionally restricted 5B left panel Expression is in the vascular smooth muscle of vessels in the cerebellum.
Specimen not shown E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: diaphragm Present Expression is at the fiber membrane.
TS26: quadriceps femoris muscle Present Expression is at the fiber membrane.
Specimen not shown P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: diaphragm Present Expression is as a smooth continuous outline around the fibers.
Specimen not shown E18 mdx: embryonic day 18.0; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS26: diaphragm Present Expression is at the periphery of fibers in uneven patches.
TS26: quadriceps femoris muscle Present Expression is at the periphery of fibers in uneven patches.
Specimen not shown P1 mdx: postnatal day 1; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS27: diaphragm Present Expression is at the periphery of fibers in uneven patches.
TS27: quadriceps femoris muscle Present Expression is at the periphery of fibers in uneven patches.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory