Wnt10aem1(cre/ERT2)Amc
Endonuclease-mediated Allele Detail
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Symbol: |
Wnt10aem1(cre/ERT2)Amc |
Name: |
wingless-type MMTV integration site family, member 10A; endonuclease-mediated mutation 1, Andrew P McMahon |
MGI ID: |
MGI:5902945 |
Synonyms: |
Wnt10a-CE, Wnt10aCRE-ERT2 |
Gene: |
Wnt10a Location: Chr1:74831178-74843335 bp, + strand Genetic Position: Chr1, 38.54 cM
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Alliance: |
Wnt10aem1(cre/ERT2)Amc page
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Germline Transmission: |
Earliest citation of germline transmission:
J:159099
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Parent Cell Line: |
JM8.N4 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Wnt10aem1(cre/ERT2)Amc expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Wnt10a (MGI:108071) |
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Mutation details: Plasmids encoding a signal guide RNA designed to introduce a cre/ERT2 knock-in mutation into near the ATG site of the Wnt10a gene and the cas9 nuclease were introduced into the cytoplasm of C57BL/6N-derived JM8.N4 ES cells.
(J:159099)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Wnt10a
(mouse)
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Original: |
J:159099 McMahon A, et al., Summary of mouse strains characterized by GUDMAP consortium. Unpublished. 2010; |
All: |
2 reference(s) |
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