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Gene Expression Data
Assay Details
Assay
Reference: J:76233 Faisst AM, et al., Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos. Mech Dev. 2002 Apr;113(1):15-28
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5902693
Gene symbol: Rttn
Gene name: rotatin
Reporter: lacZ
Direct Detection
Results
Specimen 2A +/-: embryonic day 7.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS11: embryo Weak Widespread 2A +/-
TS11: extraembryonic component Weak Widespread 2A +/-
Specimen 2A -/-: embryonic day 7.5; RttnGt(pGT1.8geo)7Pgr/RttnGt(pGT1.8geo)7Pgr (more )
Structure Level Pattern Image Note
TS11: conceptus Present 2A -/-
Specimen 2B +/-: embryonic day 8.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS13: neural plate Present Regionally restricted 2B +/-
TS13: future prosencephalon Strong Regionally restricted 2B +/- Strongest expression in telencephalon.
TS13: heart Weak 2B +/-
TS13: somite Weak 2B +/-
Specimen 2E: embryonic day 9.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 2E Expression in basal forebrain.
TS15: 1st branchial arch Present 2E
TS15: forelimb bud Present 2E
TS15: somite Present 2E
TS15: heart Absent 2E
TS15: tail Absent 2E
Specimen 2F: embryonic day 9.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS15: somite Present Regionally restricted 2F Expression in somites (particularly medial part).
TS15: forelimb bud mesenchyme Present Regionally restricted 2F
TS15: neural tube Weak 2F
TS15: notochord Weak 2F
Specimen 2G: embryonic day 9.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS15: somite Present Regionally restricted 2G Expression in somites (particularly medial part) .
TS15: forelimb bud mesenchyme Present 2G
TS15: neural tube Weak 2G
TS15: notochord Weak 2G
TS15: tail Absent 2G
Specimen 2H: embryonic day 9.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS15: telencephalon Present 2H
TS15: 1st branchial arch Present 2H
TS15: 2nd branchial arch Weak 2H
Specimen 2I: embryonic day 9.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 2I
TS15: future midbrain Present Regionally restricted 2I
TS15: 1st branchial arch Present 2I
TS15: 2nd branchial arch Weak 2I
Specimen 2J +/-: embryonic day 11.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS19: embryo mesoderm Present Regionally restricted 2J +/- Authors state that mesodermal expression pattern is maintained.
TS19: branchial arch Strong 2J +/-
TS19: heart Present 2J +/-
Specimen 3B -/-: embryonic day 9.5; RttnGt(pGT1.8geo)7Pgr/RttnGt(pGT1.8geo)7Pgr (more )
Structure Level Pattern Image Note
TS15: embryo Present 3B -/-
Specimen 3B +/-: embryonic day 9.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS15: embryo Present 3B +/-
Specimen 3H -/-: embryonic day 10.5; RttnGt(pGT1.8geo)7Pgr/RttnGt(pGT1.8geo)7Pgr (more )
Structure Level Pattern Image Note
TS17: embryo Present 3H -/-
Specimen 3H +/-: embryonic day 10.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS17: embryo Present 3H +/-
Specimen 3I -/-: embryonic day 11.5; RttnGt(pGT1.8geo)7Pgr/RttnGt(pGT1.8geo)7Pgr (more )
Structure Level Pattern Image Note
TS19: embryo Present 3I -/-
Specimen 3I +/-: embryonic day 11.5; RttnGt(pGT1.8geo)7Pgr/Rttn+ (more )
Structure Level Pattern Image Note
TS19: embryo Present 3I +/-
Specimen 5D -/-: embryonic day 8.5; RttnGt(pGT1.8geo)7Pgr/RttnGt(pGT1.8geo)7Pgr (more )
Note: Double labeled: blue - Rttn reporter; purple - Foxa2 (assay MGI:5902704).
Structure Level Pattern Image Note
TS13: neural plate Present 5D -/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory