About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:231461 Slowik AD, et al., A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae. Dev Biol. 2016 Mar 1;411(1):1-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5902117
Gene symbol: Myo6
Gene name: myosin VI
Antibody: anti-Myo6
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A: embryonic day 14.5 (more )
Note: Double labeled: green - Myo6; red - Sox2 (assay MGI:5902118).
Structure Level Pattern Image Note
TS22: saccule epithelium Present 5A Expressed in early hair cells.
TS22: utricle epithelium Present 5A Expressed in early hair cells.
TS22: semicircular canal epithelium Present Regionally restricted 5A Expressed in the anterior crista, and the posterior and horizontal cristae.
TS22: cochlear duct Absent 5A
Specimen 5C/C': embryonic day 14.5 (more )
Note: Double labeled: green - Myo6; red - Sox2 (assay MGI:5902118).
Structure Level Pattern Image Note
TS22: semicircular canal epithelium Present Regionally restricted 5C , 5C' Expressed in early hair cells in developing anterior crista. Sox2-coexpressing cells occurred in two distinct patches for each anterior and posterior crista.
Specimen 5D/D': embryonic day 14.5 (more )
Note: Double labeled: green - Myo6; red - Sox2 (assay MGI:5902118).
Structure Level Pattern Image Note
TS22: semicircular canal epithelium Present Regionally restricted 5D , 5D' Expressed in early hair cells in the horizontal crista.
Specimen 5E/E': embryonic day 14.5 (more )
Note: Double labeled: green - Myo6; red - Sox2 (assay MGI:5902118).
Structure Level Pattern Image Note
TS22: semicircular canal epithelium Present 5E' , 5E Expressed in early hair cells in developing posterior crista. Sox2-coexpressing cells occurred in two distinct patches for each anterior and posterior crista.
Specimen 5F/F': embryonic day 14.5 (more )
Note: Double labeled: green - Myo6; red - Sox2 (assay MGI:5902118).
Structure Level Pattern Image Note
TS22: saccule epithelium Present 5F' , 5F Expressed in early hair cells.
TS22: utricle Present Regionally restricted 5F , 5F' Expressed in distinct cells,but these cells did not exhibit the typical hair cell lamination.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory