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Gene Expression Data
Assay Details
Assay
Reference: J:124786 Xie M, et al., Functional implication of nucleolin in the mouse first molar development. J Biol Chem. 2007 Aug 10;282(32):23275-83
Assay type: RNA in situ
MGI Accession ID: MGI:5902039
Gene symbol: Ncl
Gene name: nucleolin
Probe: nucleolin cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A E10.5: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component ectoderm Present Regionally restricted 2A E10.5 Authors report expression in oral epithelium and mesenchyme (presumptive dental epithelium and mesenchyme of lower first molar) at tooth initiation stage of E10.5.
TS18: 1st branchial arch mandibular component mesenchyme Present Regionally restricted 2A E10.5 Authors report expression in oral epithelium and mesenchyme (presumptive dental epithelium and mesenchyme of lower first molar) at tooth initiation stage of E10.5.
Specimen 2A E12.0: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mandible primordium Present Regionally restricted 2A E12.0 Expression in thickened oral/dental epithelium and in underlying dental mesenchyme of lower first molar at early bud stage.
Specimen 2A E14.0: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar epithelium Present Regionally restricted 2A E14.0
TS22: tooth bud Present Regionally restricted 2A E14.0
Specimen 2A E15.0: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cap stage tooth Present Regionally restricted 2A E15.0
TS23: lower jaw molar enamel organ Strong Regionally restricted 2A E15.0 Strong expression in epithelial cells of enamel organ.
TS23: enamel knot Absent 2A E15.0 No expression in the primary enamel knot (PEK) area.
Specimen 2A E16.0: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: early bell stage tooth Present Regionally restricted 2A E16.0
TS24: lower jaw molar enamel organ Present Regionally restricted 2A E16.0 Strong expression in inner enamel epitheium, cervical loop, and part of outer enamel epithelial cells.
TS24: cervical loop Strong 2A E16.0
TS24: lower jaw molar dental papilla Present 2A E16.0
Specimen 2A E17.0: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: mid bell stage tooth Present Regionally restricted 2A E17.0
TS25: lower jaw molar dental papilla Present Regionally restricted 2A E17.0 Expression restricted to inner enamel epithelium and cusp areas of dental papilla.
TS25: lower jaw molar enamel organ Present Regionally restricted 2A E17.0 Expression restricted to inner enamel epithelium and cusp areas of dental papilla.
Specimen 2A E18.0: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: late bell stage tooth Present Regionally restricted 2A E18.0
TS26: lower jaw molar dental papilla Present Regionally restricted 2A E18.0 Expression restricted to inner enamel epithelium and cusp areas of dental papilla.
TS26: lower jaw molar enamel organ Present Regionally restricted 2A E18.0 Expression restricted to inner enamel epithelium and cusp areas of dental papilla.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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