Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Lck-cre)14Syt
Name:	Transgenic insertion 14, Huey-Kang Sytwu
MGI ID:	MGI:5901740
Synonyms:	Tg(Lck-cre)14Sytwu
Transgene:	Tg(Lck-cre)14Syt  Location: unknown
Alliance:	Tg(Lck-cre)14Syt page

Strain of Origin:

NOD/ShiLtJSyt

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Lck-cre)14Syt expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Lck   Mutation details: A transgene construct containing proximal lymphocyte protein tyrosine kinase (Lck) promoter driving cre recombinase was used to create transgenic line in NOT/Sytwu mouse. At least two lines 7 and 14 were made. Cre recombinase is expressed in a T-cell specific manner. (J:194560, J:202955)

Activity:	Tissue activity of this recombinase allele
Driver:	Lck (species not specified) Summary of all recombinase alleles driven by Lck.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:194560 Lin MH, et al., B lymphocyte-induced maturation protein 1 (BLIMP-1) attenuates autoimmune diabetes in NOD mice by suppressing Th1 and Th17 cells. Diabetologia. 2013 Jan;56(1):136-46
All:	3 reference(s)