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Gene Expression Data
Assay Details
Assay
Reference: J:46130 Nakayama A, et al., Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev. 1998 Jan;70(1-2):155-66
Assay type: RNA in situ
MGI Accession ID: MGI:5898554
Gene symbol: Dct
Gene name: dopachrome tautomerase
Probe: clone p5A7
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3D: embryonic day 11.5; Mitfmi-ew/Mitfmi-ew (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent 3D Dct

Specimen 3E: embryonic day 11.5; Mitfmi-ew/Mitfmi-ew (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent 3E Dct

Specimen 3F: embryonic day 11.5; Mitfmi-ew/Mitfmi-ew (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Absent 3F Dct

Specimen 5D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 5D Expression in cells in concentrated in a small area representing the presumptive stria vascularis in future cochlear duct.

Specimen at birth not shown: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: stria vascularis Present

Specimen 9 wt: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: migrating neural crest Present 9_Dct wt
TS22: pigmented retinal epithelium Present 9_Dct wt

Specimen 9 Mi-wh: embryonic day 14.5; MitfMi-wh/MitfMi-wh (more )
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Present 9_Dct Mi-wh Expression barely affected compared to wild type embryos.
TS22: migrating neural crest Absent 9_Dct Mi-wh

Specimen 9 mi: embryonic day 14.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Weak 9_Dct mi
TS22: migrating neural crest Absent 9_Dct mi

Specimen 9 mi-ew: embryonic day 14.5; Mitfmi-ew/Mitfmi-ew (more )
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Weak 9_Dct mi-ew
TS22: migrating neural crest Absent 9_Dct mi-ew


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory