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Tg(Cela1-cre/Ers1*)49Cns
Transgene Detail
Summary
Symbol: Tg(Cela1-cre/Ers1*)49Cns
Name: Transgene insertion 49, Chia-Ning Shen
MGI ID: MGI:5898048
Synonyms: Elas-CreER, Tg(Elas-CreER)49Cns
Transgene: Tg(Cela1-cre/Ers1*)49Cns  Location: unknown  
Alliance: Tg(Cela1-cre/Ers1*)49Cns page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Cela1-cre/Ers1*)49Cns expression driven by 1 gene
 
Mutation detailsThe construct used to create Tg(Cela1-cre/ERT)1Dam was used to generate this transgenic mouse line. The construct contained a fused 200 bp enhancer of the elastase gene to a minimal hsp68 promoter followed by CreER coding sequence. Five founders were identified that showed acinar-specific expression. (J:102226, J:241207)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cela1 (species not specified)
Summary of all recombinase alleles driven by Cela1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:241207 Wu SY, et al., Differentiation of pancreatic acinar cells to hepatocytes requires an intermediate cell type. Gastroenterology. 2010 Jun;138(7):2519-30
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory