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Tg(Slc6a3-EGFP/Rpl10a)I17-11Pggd
Transgene Detail
Summary
Symbol: Tg(Slc6a3-EGFP/Rpl10a)I17-11Pggd
Name: transgene insertion I17-11, Paul Greengard
MGI ID: MGI:5897802
Synonyms: Dat bacTRAP
Transgene: Tg(Slc6a3-EGFP/Rpl10a)I17-11Pggd  Location: unknown  
Alliance: Tg(Slc6a3-EGFP/Rpl10a)I17-11Pggd page
Transgene
origin
Strain of Origin:  C57BL/6NCrl
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe mouse BAC (bacterial artificial chromosome) RP24-269I17 containing the entire Slc6a3 gene, was modified by inserting cDNA encoding EGFP/Rpl10a (Enhanced Green Fluorescent Protein fused to ribosomal protein L10A) and a 3' polyA sequence upstream of the endogenous Slc6a3 ATG initiating codon. EGFP expressionis detected in dopaminergic cell bodies and does not extend to the projections of these neurons. (J:241067)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:241067 Brichta L, et al., Identification of neurodegenerative factors using translatome-regulatory network analysis. Nat Neurosci. 2015 Sep;18(9):1325-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory