Gene Expression Data
Assay Details
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Assay
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Reference:
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J:21056
Jernvall J, et al., Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non-dividing cells express growth stimulating Fgf-4 gene. Int J Dev Biol. 1994 Sep;38(3):463-9
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5897300
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Gene symbol:
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Fgf4
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Gene name:
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fibroblast growth factor 4
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Results
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Specimen
not shown:
embryonic day 13.5
(more  )
Specimen
not shown:
(close  )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
1A:
embryonic day 14.5
(more )
Specimen
1A:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: enamel knot |
Very strong |
Regionally restricted |
1A
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Very strong and sharply delineated expression was detected in the enamel knot.
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| TS22: lower jaw molar enamel organ |
Very strong |
Regionally restricted |
1A
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Very strong and sharply delineated expression was detected in the enamel knot.
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Specimen
1B:
embryonic day 14.5
(more )
Specimen
1B:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: enamel knot |
Very strong |
Regionally restricted |
1B
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Incisors had similar expression to molars in their enamel knots.
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| TS22: lower jaw incisor enamel organ |
Very strong |
Regionally restricted |
1B
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Incisors had similar expression to molars in their enamel knots.
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Specimen
1C/D:
embryonic day 18.5
(more )
Specimen
1C/D:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: enamel knot |
Present |
Regionally restricted |
1C/D
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Expression was transiently present in the epithelial cells at the future cusp tip, co-localizing with non-proliferative areas called secondary enamel knots.
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| TS26: lower jaw molar enamel organ |
Present |
Regionally restricted |
1C/D
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Expression was transiently present in the epithelial cells at the future cusp tip, co-localizing with non-proliferative areas called secondary enamel knots.
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Specimen
2B:
embryonic day 14.5
(more )
Note: Cap stage.
Specimen
2B:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Cap stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: enamel knot |
Very strong |
Regionally restricted |
2B
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Very strong and sharply delineated expression was detected in the enamel knot.
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| TS22: lower jaw molar enamel organ |
Very strong |
Regionally restricted |
2B
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Very strong and sharply delineated expression was detected in the enamel knot.
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Specimen
2D:
embryonic day 16.5
(more )
Note: Bell stage.
Specimen
2D:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Bell stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: enamel knot |
Present |
Regionally restricted |
2D
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Expression was transiently present in the epithelial cells at the future cusp tip, co-localizing with non-proliferative areas called secondary enamel knots.
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| TS24: lower jaw molar enamel organ |
Present |
Regionally restricted |
2D
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Expression was transiently present in the epithelial cells at the future cusp tip, co-localizing with non-proliferative areas called secondary enamel knots.
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Analysis Tools