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Cdh13tm1(cre/ERT2)Jrs
Targeted Allele Detail
Summary
Symbol: Cdh13tm1(cre/ERT2)Jrs
Name: cadherin 13; targeted mutation 1, Joshua R Sanes
MGI ID: MGI:5896332
Synonyms: Cdh13CreER
Gene: Cdh13  Location: Chr8:119010472-120051660 bp, + strand  Genetic Position: Chr8, 65.97 cM
Alliance: Cdh13tm1(cre/ERT2)Jrs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:235958
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Cdh13tm1(cre/ERT2)Jrs expression driven by 1 gene
 
Mutation details: The targeting vector, consisting of a FRT-flanked neomycin selection cassette, a 6xmyc-tagged CreER-T2 recombinase cDNA, and polyadenylation signal, replaced N-term 15 amino acid at the translational start site of the mouse Cdh13 gene via homologous recombination. FLP-mediated recombination in the germline removed the FRT-flanked neomycin selection cassette. (J:230646, J:235958)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cdh13 (mouse)
Summary of all recombinase alleles driven by Cdh13.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh13 Mutation:  30 strains or lines available
References
Original:  J:230646 Poliak S, et al., Muscle-type Identity of Proprioceptors Specified by Spatially Restricted Signals from Limb Mesenchyme. Cell. 2016 Jan 28;164(3):512-25
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory