Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Npy1rtm1(cre/GFP)Rpa
Name:	neuropeptide Y receptor Y1; targeted mutation 1.1, Richard D Palmiter
MGI ID:	MGI:5896318
Gene:	Npy1r  Location: Chr8:67149844-67159444 bp, + strand  Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
Alliance:	Npy1rtm1(cre/GFP)Rpa page

Germline Transmission:	Earliest citation of germline transmission: J:234810
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Npy1rtm1(cre/GFP)Rpa expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Npy1r (MGI:104963)   Mutation details: IRES-Myc tag-nuclear localization signal (NLS)-cre-GFP-frt-neomycin-frt were introduced just before the initiation codon of the mouse Npy1r gene via homologous recombination. The frt-flanked neomycin cassette is retained, but cre recombinase is still expressed. (J:234810)

Activity:	Tissue activity of this recombinase allele
Driver:	Npy1r (mouse) Summary of all recombinase alleles driven by Npy1r. Alliance mouse Npy1r gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npy1r Mutation:	25 strains or lines available

Original:	J:234810 Padilla SL, et al., Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state. Nat Neurosci. 2016 May;19(5):734-41
All:	1 reference(s)