Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Rprd1bTg(CAG-cre/Esr1*)32Ichi
Name:	regulation of nuclear pre-mRNA domain containing 1B; transgene insertion 32, Hirotake Ichise
MGI ID:	MGI:5888987
Synonyms:	Rprd1bC32delta
Gene:	Rprd1b  Location: Chr2:157870395-157920127 bp, + strand  Genetic Position: Chr2, 78.72 cM, cytoband H2
Alliance:	Rprd1bTg(CAG-cre/Esr1*)32Ichi page

Germline Transmission:	Earliest citation of germline transmission: J:240153
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Rprd1bTg(CAG-cre/Esr1*)32Ichi expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note chicken CAG   Mutation details: The transgene construct consisting of truncated CAG promoter followed by CreMer fusion protein and truncated Pgk poly-A was inserted into the intorn 3 of Rprd1b gene. Rprd1b is created by FLP-mediated excision of GFP/neo fusion gene from the conditional transgene Rprd1b. After FLP-mediated excision, tissue-specific expression of inducible cre is detected. (J:240153)

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rprd1b Mutation:	16 strains or lines available

Original:	J:240153 Ichise H, et al., Establishment of a tamoxifen-inducible Cre-driver mouse strain for widespread and temporal genetic modification in adult mice. Exp Anim. 2016 Jul 29;65(3):231-44
All:	1 reference(s)