Rprd1bTg(CAG-GFP/neo*,-cre/Esr1*)32Ichi
Transgenic Allele Detail
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| Symbol: |
Rprd1bTg(CAG-GFP/neo*,-cre/Esr1*)32Ichi |
| Name: |
regulation of nuclear pre-mRNA domain containing 1B; transgene insertion 32, Hirotake Ichise |
| MGI ID: |
MGI:5888985 |
| Synonyms: |
Rprd1bCM32, Rprd1bTg(CAG-GFPneo*, -Cre/Esr1*)32Ichi |
| Gene: |
Rprd1b Location: Chr2:157870395-157920127 bp, + strand Genetic Position: Chr2, 78.72 cM, cytoband H2
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| Alliance: |
Rprd1bTg(CAG-GFP/neo*,-cre/Esr1*)32Ichi page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:240153
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| Parent Cell Line: |
E14.1 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Transgene Type: |
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Transgenic (Conditional ready, Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Rprd1bTg(CAG-GFP/neo*,-cre/Esr1*)32Ichi expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: The transgene construct consisting of truncated CAG promoter and FRT-flanked modified GFP/neo fusion gene followed by CreMer fusion protein and truncated Pgk poly-A was inserted into the intron 3 of Rprd1b gene. Prior to FLP-mediated excision of the FRT-flanked GFP/neo fusion gene, expression of GFP/neo is observed in various tissues. By breeding to Flip recombinase expressing mice, Rprd1b transgenic line was generated by removing GFP/neo fusion gene.
(J:240153)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rprd1b Mutation: |
14 strains or lines available
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| Original: |
J:240153 Ichise H, et al., Establishment of a tamoxifen-inducible Cre-driver mouse strain for widespread and temporal genetic modification in adult mice. Exp Anim. 2016 Jul 29;65(3):231-44 |
| All: |
1 reference(s) |
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