Gene Expression Data
Assay Details
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Assay
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Reference:
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J:121792
Mizuta K, et al., Molecular characterization of GDD1/TMEM16E, the gene product responsible for autosomal dominant gnathodiaphyseal dysplasia. Biochem Biophys Res Commun. 2007 May 25;357(1):126-32
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5883259
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Gene symbol:
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Ano5
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Gene name:
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anoctamin 5
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Results
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Specimen
3A GDD1:
postnatal adult
(more  )
Specimen
3A GDD1:
(close  )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cardiac muscle tissue |
Present |
Regionally restricted |
3A GDD1
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Expression confined to myofibers; appears to be associated with both cytoplasmic and subsarcolemmal vesicle-like structures.
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Specimen
3B GDD1:
postnatal adult
(more )
Specimen
3B GDD1:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: epiphyseal plate |
Present |
Regionally restricted |
3B GDD1
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Expression in femoral head cartilage, exclusively in the epiphyseal growth plate.
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| TS28: femur |
Present |
Regionally restricted |
3B GDD1
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Expression in femoral head cartilage, exclusively in the epiphyseal growth plate.
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Specimen
3C GDD1:
postnatal adult
(more )
Specimen
3C GDD1:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: epiphyseal plate hypertrophic zone |
Present |
Regionally restricted |
3C GDD1
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Expression in hypertrophic chondrocytes.
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| TS28: bone |
Present |
Regionally restricted |
3C GDD1
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Expression in osteoblasts lining the trabecular bones.
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Specimen
3D GDD1 (left):
postnatal adult
(more )
Specimen
3D GDD1 (left):
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: bone |
Present |
Regionally restricted |
3D GDD1 (left panel)
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Expression in osteoblasts lining the bone surfaces. Expression in endosteal and periosteal osteoblasts.
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Specimen
3D GDD1 (right):
postnatal adult
(more )
Specimen
3D GDD1 (right):
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cartilaginous joint |
Present |
Regionally restricted |
3D GDD1 (right panel)
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Expression in articular cartilage cells.
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Specimen
E14.5 not shown:
embryonic day 14.5
(more )
Specimen
E14.5 not shown:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3E GDD1:
embryonic day 18.5
(more )
Specimen
3E GDD1:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tibia |
Present |
Regionally restricted |
3E GDD1
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Specimen
E18.5 not shown:
embryonic day 18.5
(more )
Specimen
E18.5 not shown:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: femur |
Present |
Regionally restricted |
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Expression in growth plates of proximal tibia and distal femur.
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| TS26: tibia |
Present |
Regionally restricted |
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Expression in growth plates of proximal tibia and distal femur.
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Specimen
S4 GDD1:
embryonic day 18.5
(more )
Specimen
S4 GDD1:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tibia |
Present |
Regionally restricted |
S4_GDD1
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Expression in distal growth plate of tibia, mainly in prehypertrophic zone chondrocytes. Weaker expression in resting zone chondrocytes.
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Analysis Tools