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Gene Expression Data
Assay Details
Assay
Reference: J:21479 Johnson SE, et al., Expression of epidermal growth factor family gene members in early mouse development. Dev Dyn. 1994 Nov;201(3):216-26
Assay type: RNA in situ
MGI Accession ID: MGI:5883010
Gene symbol: Cripto
Gene name: cripto, EGF-CFC family member
Probe: p4A22-17
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4A/C: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Weak 4A/C
Specimen 4B/D: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: inner cell mass Weak 4B/D
TS4: trophectoderm Weak 4B/D
Specimen 5A/B: embryonic day 5.5 (more )
Note: egg cylinder stage
Structure Level Pattern Image Note
TS7: epiblast Present Regionally restricted 5A/B Expression concentrated in the embryonic ectoderm.
TS7: extraembryonic ectoderm Absent 5A/B
Specimen 5C/D: embryonic day 6.5 (more )
Note: gastrula stage
Structure Level Pattern Image Note
TS9: embryo ectoderm Present 5C/D Expression concentrated in the embryonic ectoderm.
TS9: extraembryonic component Absent 5C/D No expression detected outside of the embryo proper.
Specimen 6B/E: embryonic day 7.25 (more )
Note: primitive streak stage
Structure Level Pattern Image Note
TS10: embryo mesoderm Present Regionally restricted 6B/E Expression localized in the primitive streak ectoderm and mesodermal tissue arising from it.
TS10: primitive streak Present Regionally restricted 6B/E Expression localized in the primitive streak ectoderm and mesodermal tissue arising from it.
TS10: extraembryonic component Absent 6B/E
Specimen 6C/F: embryonic day 7.5 (more )
Note: neural plate, presomite stage
Structure Level Pattern Image Note
TS11: extraembryonic component Strong Regionally restricted 6C/F High level of expression in extraembryonic tissues, including extraembryonic ectoderm, extraembryonic mesoderm, and ectoplacental cone.
TS11: ectoplacental cone Present 6C/F
TS11: extraembryonic ectoderm Present 6C/F
TS11: extraembryonic mesoderm Present 6C/F
Specimen 7A/C: embryonic day 7.25 (more )
Note: primitive streak stage
Structure Level Pattern Image Note
TS10: embryo mesoderm Present Regionally restricted 7A/C Expression in mesoderm egressing from the primitive streak.
Specimen 8A/B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present 8A/B Expression restricted to epimyocardium of the developing heart tubes.
TS13: endocardial tube Absent 8A/B No expression in the endocardium.
Specimen 8C/D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: outflow tract Present Regionally restricted 8C/D Expression restricted to the outflow region of the heart
TS15: cardiac muscle tissue Present Regionally restricted 8C/D Expression localized in the myocardium.
TS15: endocardial lining Absent 8C/D No expression in the endocardium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory