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Gene Expression Data
Assay Details
Assay
Reference: J:25544 Simeone A, et al., Expression of runt in the mouse embryo. Dev Dyn. 1995 May;203(1):61-70
Assay type: RNA in situ
MGI Accession ID: MGI:5882377
Gene symbol: Runx1
Gene name: runt related transcription factor 1
Probe: pGmmr1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2a/a': embryonic day 8.2 (more )
Structure Level Pattern Image Note
TS12: embryo Absent 2a/a'
TS28: decidua Strong Regionally restricted 2a/a' Expressed in the decidua surrounding the implantation zone, particularly in the outer zone.

Specimen 2b/b': embryonic day 9.2 (more )
Structure Level Pattern Image Note
TS14: dorsal aorta Present 2b/b'
TS14: nephrogenic cord Present 2b/b'

Specimen 2c/c': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: olfactory epithelium Strong Regionally restricted 2c/c' Expressed in the basal layer.
TS20: tongue Strong Regionally restricted 2c/c' Expressed in the dorsal part.
TS20: genital tubercle Present 2c/c'
TS20: pancreas Present 2c/c'
TS20: spinal cord Present 2c/c'
TS20: cartilage condensation Present 2c/c' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.
TS20: gonad Strong Regionally restricted 2c/c' Expressed at the tip and at the dorsal aspect of the genital tubercle.

Specimen 2d/d': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present 2d/d'
TS20: dorsal root ganglion Strong 2d/d'
TS20: vibrissa follicle Strong 2d/d'
TS20: cartilage condensation Present 2d/d' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 2e/e': embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Strong 2e/e'
TS22: Meckel's cartilage Present 2e/e'
TS22: genital tubercle Present 2e/e'
TS22: inner ear Present 2e/e'
TS22: trigeminal ganglion Present 2e/e'
TS22: olfactory epithelium Strong Regionally restricted 2e/e' Expressed in the basal layer.
TS22: cartilage condensation Present 2e/e' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.
TS22: gonad Strong Regionally restricted 2e/e' Expressed at the tip and at the dorsal aspect of the genital tubercle.

Specimen 2f/f': embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Strong 2f/f'
TS22: vibrissa follicle Strong 2f/f'
TS22: chondrocranium cartilage condensation Present 2f/f' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 2g/g': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: femur pre-cartilage condensation Present 2g/g'
TS20: vomeronasal organ Present 2g/g'
TS20: vibrissa follicle Strong 2g/g'
TS20: olfactory epithelium Strong Regionally restricted 2g/g' Expressed in the basal layer.
TS20: cartilage condensation Present 2g/g' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 2h/h': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: Meckel's cartilage Present 2h/h'
TS20: trigeminal ganglion Present 2h/h'
TS20: olfactory epithelium Strong Regionally restricted 2h/h' Expressed in the basal layer.
TS20: cartilage condensation Present 2h/h' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 2i/i': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 2i/i' The strongest signal is subluminal, in a position corresponding to the ventrolateral region of the matrix layer, which contains proliferating neuroblasts, and extends radially to the outer surface of the neural tube.
TS20: dorsal root ganglion Strong 2i/i'
TS20: cartilage condensation Present 2i/i' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 2j/j': embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Strong Regionally restricted 2j/j' Expressed in the basal layer.
TS22: genital tubercle Present 2j/j'
TS22: vibrissa follicle Strong 2j/j'
TS22: cartilage condensation Present 2j/j' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.
TS22: gonad Strong Regionally restricted 2j/j' Expressed at the tip and at the dorsal aspect of the genital tubercle.

Specimen 2k/k': embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present 2k/k'
TS22: cartilage condensation Present 2k/k' Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 2l/l': embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Strong 2l/l'

Specimen 3A/B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: olfactory placode Present 3A/B

Specimen 3C/D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 3C/D
TS17: 2nd branchial arch Present 3C/D
TS17: 3rd branchial arch Present 3C/D
TS17: 4th branchial arch Present 3C/D

Specimen 3E/F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 2nd branchial arch Present 3E/F
TS17: 3rd branchial arch Present 3E/F

Specimen 4A/B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Strong Regionally restricted 4A/B Bilaterally expressed in presumptive precursors of motor neurons and a more dorso-lateral region.

Specimen 4C/D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 4C/D Expressed with a rostral boundary at the level of the junction between the hindbrain and the spinal cord and a caudal boundary corresponding approximately to the 8-10 somite, i.e., to the level of the forelimb bud.
TS17: somite Present 4C/D

Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 5A The strongest signal is subluminal, in a position corresponding to the ventrolateral region of the matrix layer, which contains proliferating neuroblasts, and extends radially to the outer surface of the neural tube.

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: choroid plexus Present 5B

Specimen 5C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: facial ganglion Present 5C
TS20: glossopharyngeal ganglion Present 5C
TS20: trigeminal ganglion Present 5C
TS20: vagus ganglion Present 5C
TS20: vestibulo-cochlear ganglion Present 5C
TS20: vibrissa follicle Strong 5C
TS20: olfactory epithelium Strong Regionally restricted 5C Expressed in the basal layer.
TS20: cartilage condensation Present 5C Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 5D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Strong 5D
TS20: cartilage condensation Present 5D Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 5E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: Meckel's cartilage Present 5E
TS20: trigeminal ganglion Present 5E
TS20: nasal process Present Regionally restricted 5E Expressed in nasal capsule and basisphenoid chondrogenic centre.
TS20: nasal cavity mucosa Present Regionally restricted 5E Expressed in olfactory mucosa.
TS20: vibrissa follicle Strong 5E
TS20: olfactory epithelium Strong Regionally restricted 5E Expressed in the basal layer.
TS20: cartilage condensation Present 5E Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 5F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nasal septum Present 5F
TS20: primary palate Strong Regionally restricted 5F Expressed in the focal areas.
TS20: nasal process Present Regionally restricted 5F Expressed in nasal capsule.
TS20: cartilage condensation Present 5F Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.

Specimen 6A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diaphragm Present 6A
TS20: urogenital ridge Present Regionally restricted 6A Expressed in the gonadal blastema, on the medial aspect of the urogenital ridge.
TS20: paramesonephric duct Strong 6A

Specimen 6B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: vertebral cartilage condensation Present Regionally restricted 6B Expressed in the vertebral centra.
TS20: gonad Strong Regionally restricted 6B Expressed at the tip and at the dorsal aspect of the genital tubercle.

Specimen 6C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: thymus Strong 6C More strongly expressed in the cortex.
TS25: heart atrium Present 6C
TS25: trachea Present 6C

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Present Expressed in the tooth germs.
TS20: esophagus Present
TS20: gastro-esophageal junction Present
TS20: lung Present
TS20: stomach Present
TS20: thymus primordium Present

Specimen not shown: embryonic day 13.5 (more )
Note: Fig. 5 showed expression of E12.5-13.5.
Structure Level Pattern Image Note
TS21: central nervous system Present Regionally restricted The strongest signal is subluminal, in a position corresponding to the ventrolateral region of the matrix layer, which contains proliferating neuroblasts, and extends radially to the outer surface of the neural tube.
TS21: Meckel's cartilage Present
TS21: choroid plexus Present
TS21: dorsal root ganglion Present
TS21: facial ganglion Present
TS21: glossopharyngeal ganglion Present
TS21: nasal capsule Present
TS21: nasal septum Present
TS21: trigeminal ganglion Present
TS21: vagus ganglion Present
TS21: vestibulo-cochlear ganglion Present
TS21: vibrissa follicle Present
TS21: olfactory epithelium Present Regionally restricted Expressed in the basal layer.
TS21: cartilage condensation Present Expressed in all skeletal chondrogenic centres in the head, trunk, limbs, and tail.
TS21: nasal cavity mucosa Present Regionally restricted Expressed in olfactory mucosa.
TS21: sphenoid bone pre-cartilage condensation Present

Specimen not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: esophagus Present
TS22: gastro-esophageal junction Present
TS22: lung Present
TS22: stomach Present
TS22: thymus primordium Present
TS22: tooth bud Present

Specimen not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: submandibular gland Present
TS25: thyroid gland Present Fainter expression.
TS25: embryo Present Expression largely persisted.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory