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Gene Expression Data
Assay Details
Assay
Reference: J:237216 Oetjen S, et al., Revisiting the neuronal localization and trafficking of CLN3 in juvenile neuronal ceroid lipofuscinosis. J Neurochem. 2016 Nov;139(3):456-470
Assay type: RNA in situ
MGI Accession ID: MGI:5881963
Gene symbol: Cln3
Gene name: CLN3 lysosomal/endosomal transmembrane protein, battenin
Probe: Cln3 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1a E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: embryo Present Ubiquitous 1a E12
TS20: nervous system Strong 1a E12

Specimen 1a E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: embryo Present Ubiquitous 1a E14
TS22: cerebral cortex Strong 1a E14
TS22: thalamus Strong 1a E14
TS22: heart Strong 1a E14
TS22: nervous system Strong 1a E14

Specimen 1a E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: embryo Present Ubiquitous 1a E16
TS24: cerebral cortex Strong 1a E16
TS24: pituitary gland Strong 1a E16
TS24: thalamus Strong 1a E16
TS24: medulla oblongata Moderate 1a E16
TS24: duodenum Strong 1a E16
TS24: heart Strong 1a E16
TS24: lung Strong 1a E16
TS24: metanephros Strong 1a E16
TS24: nasal cavity Strong 1a E16
TS24: submandibular gland Strong 1a E16
TS24: thymus Strong 1a E16

Specimen 1a E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: embryo Present Ubiquitous 1a E18
TS26: brain Weak 1a E18 Decreased expression levels in the brain.
TS26: main olfactory bulb Moderate 1a E18
TS26: duodenum Strong 1a E18
TS26: lung Strong 1a E18
TS26: nasal cavity Strong 1a E18
TS26: submandibular gland Strong 1a E18

Specimen 1b P3 (top): postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: brain Weak Regionally restricted 1b P3 (top) Decreased expression levels in the brain.
TS27: hippocampus Present 1b P3 (top)

Specimen 1b P3 (bottom): postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cerebellum Present 1b P3 (bottom) Relatively higher levels of expression only in areas of high cell density, such as the hippocampus and cerebellum.
TS27: hippocampus Present 1b P3 (bottom) Relatively higher levels of expression only in areas of high cell density, such as the hippocampus and cerebellum.

Specimen 1b P7 (top): postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 1b P7 (top) Relatively higher levels of expression only in areas of high cell density, such as the hippocampus and cerebellum.

Specimen 1b P7 (bottom): postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: brain Weak Regionally restricted 1b P7 (bottom) Decreased expression levels in the brain.

Specimen 1b P21 (top): postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 1b P21 (top) Relatively higher levels of expression only in areas of high cell density, such as the hippocampus and cerebellum.

Specimen 1b P21 (bottom): postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 1b P21 (bottom) Relatively higher levels of expression only in areas of high cell density, such as the hippocampus and cerebellum.

Specimen 1b adult (top left): postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 1b adult (top left) Relatively higher levels of expression only in areas of high cell density, such as the hippocampus and cerebellum.

Specimen 1b adult (top right): postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 1b adult (top right) Relatively higher levels of expression only in areas of high cell density, such as the hippocampus and cerebellum.

Specimen 1b adult (middle right): postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain Trace Regionally restricted 1b adult (middle right) Authors report strongly reduced expression; expression was hardly detectable.

Specimen 1b adult (bottom): postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 1b adult (bottom) Relatively higher levels of expression only in areas of high cell density, such as the hippocampus and cerebellum.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory