Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc44a2tm1.1Tec
Name:	solute carrier family 44, member 2; targeted mutation 1.1, Thomas E Carey
MGI ID:	MGI:5828929
Synonyms:	Slc44a2flox
Gene:	Slc44a2  Location: Chr9:21232015-21266324 bp, + strand  Genetic Position: Chr9, 7.77 cM
Alliance:	Slc44a2tm1.1Tec page

Germline Transmission:	Earliest citation of germline transmission: J:239440
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A targeting vector containing an FRT-flanked PGK-Neo selection cassette followed by a loxP site inserted upstream of exon 3 and another loxP site was inserted downstream of exon 10. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 3 through 10 floxed. (J:239440)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc44a2 Mutation:	48 strains or lines available

Original:	J:239440 Kommareddi P, et al., Hair Cell Loss, Spiral Ganglion Degeneration, and Progressive Sensorineural Hearing Loss in Mice with Targeted Deletion of Slc44a2/Ctl2. J Assoc Res Otolaryngol. 2015 Dec;16(6):695-712
All:	2 reference(s)