About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:172983 Kobayashi H, et al., Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects. Mech Dev. 2007 Apr;124(4):290-303
Assay type: RNA in situ
MGI Accession ID: MGI:5828465
Gene symbol: Pax2
Gene name: paired box 2
Probe: Pax2 probe29
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3S: embryonic day 10.5; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present 3S
TS17: nephric duct Present 3S
Specimen 3T: embryonic day 10.5; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS17: nephric duct Present 3T
TS17: metanephric mesenchyme Weak 3T
Specimen 3U: embryonic day 10.5; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS17: nephric duct Present 3U
TS17: metanephric mesenchyme Absent 3U
Specimen 4J: embryonic day 10.0; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS16: nephric duct Present 4J Expression in Wolffian duct.
TS16: genitourinary system Present Scattered 4J Expression detected in metanephric mesenchyme.
Specimen 4K: embryonic day 10.0; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS16: nephric duct Present 4K Expression in Wolffian duct.
TS16: genitourinary system Present Regionally restricted 4K Expression detected in metanephric mesenchyme.
Specimen 4L: embryonic day 10.0; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS16: nephric duct Present 4L Expression in Wolffian duct.
TS16: genitourinary system Present Regionally restricted 4L No expression in metanephric mesenchyme.
Specimen 6G: embryonic day 9.5; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord Present 6G Expression in nephrogenic cord.
Specimen 6H: embryonic day 9.5; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord Absent 6H
Specimen 6I: embryonic day 9.5; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord Absent 6I No expression in nephrogenic cord.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory