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Gene Expression Data
Assay Details
Assay
Reference: J:24498 Reponen P, et al., 92-kDa type IV collagenase and TIMP-3, but not 72-kDa type IV collagenase or TIMP-1 or TIMP-2, are highly expressed during mouse embryo implantation. Dev Dyn. 1995 Apr;202(4):388-96
Assay type: RNA in situ
MGI Accession ID: MGI:5828109
Gene symbol: Timp3
Gene name: tissue inhibitor of metalloproteinase 3
Probe: Timp3 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Two probes were described: MGI:5828090 and MGI:5828091.
Results
Specimen 1D/E,F: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS8: embryo Absent 1F , 1D/E

Specimen 1D/E maternal: postnatal adult (more )
Note: Pregnant uterus at 5.5 days of gestation.
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 1D/E Intense expression was observed in maternal cells in the area of the decidual reaction surrounding the egg cylinder.
TS28: uterus stroma Absent 1D/E The uterine stroma further away from the implantation site was absent.

Specimen 2D/E,F: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS8: embryo Absent 2D/E , 2F

Specimen 2D/E maternal: postnatal adult (more )
Note: Pregnant uterus at 6.5 days of gestation.
Structure Level Pattern Image Note
TS28: decidua Present 2D/E Expression was the same as at E5.5.

Specimen 3D/E,F maternal: postnatal adult (more )
Note: Pregnant uterus at 7.5 days of gestation.
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 3D/E , 3F The intensity of the earlier signal had reduced considerably. Only a few positive cells were observed in the immediate vicinity of the embryo.
TS28: uterus stroma Absent 3D/E

Specimen not shown: postnatal adult (more )
Note: Non-pregnant uterus.
Structure Level Pattern Image Note
TS28: uterus Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory