Gene Expression Data
Assay Details
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Assay
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Reference:
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J:16389
Gendron-Maguire M, et al., Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell. 1993 Dec 31;75(7):1317-31
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5824997
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Gene symbol:
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Nefm
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Gene name:
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neurofilament, medium polypeptide
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Results
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Specimen
4A:
embryonic day 10.5
(more  )
Specimen
4A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4B:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6J
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Mutant Allele(s):
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Hoxa2tm1Grid/Hoxa2tm1Grid
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: cranial nerve |
Present |
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4B
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The proximal portion of the glossopharyngeal (IX) nerve was absent. A condensation or collapse of the multiple branches of the vagus (X) nerve was seen.
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| TS17: glossopharyngeal ganglion |
Present |
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4B
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A patch of positive cells was observed just caudal to the second branchial arch, representing placodally-derived cells that contribute to the formation of the petrosal ganglion.
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Specimen
4C:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6J
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Mutant Allele(s):
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Hoxa2tm1Grid/Hoxa2tm1Grid
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: cranial nerve |
Present |
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4C
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The proximal portion of the glossopharyngeal (IX) nerve was absent.
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| TS17: glossopharyngeal ganglion |
Present |
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4C
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A patch of positive cells was observed just caudal to the second branchial arch, representing placodally-derived cells that contribute to the formation of the petrosal ganglion.
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Specimen
not shown:
embryonic day 9.5
(more )
Specimen
not shown:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
not shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6J
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Mutant Allele(s):
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Hoxa2tm1Grid/Hoxa2tm1Grid
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: embryo |
Present |
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No distinct differences were noted between homozygous mutant embryos and their heterozygous and wild-type littermates.
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Analysis Tools
