Gene Expression Data
Assay Details
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Assay
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Reference:
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J:204477
Sassa T, et al., Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production. Mol Cell Biol. 2013 Jul;33(14):2787-96
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5824528
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Gene symbol:
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Ivl
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Gene name:
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involucrin
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Probe:
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Ivl cDNA1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
S4 +/+:
embryonic day 18.5
(more  )
Specimen
S4 +/+:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: epidermis granular layer |
Strong |
Regionally restricted |
S4_Ivl +/+
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Highest expression in late differentiated keratinocytes.
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Specimen
S4 -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL * C57BL/6J * DBA
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Mutant Allele(s):
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Elovl1tm1.1Akih/Elovl1tm1.1Akih
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: epidermis granular layer |
Strong |
Regionally restricted |
S4_Ivl -/-
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Highest expression in late differentiated keratinocytes. Expression was unaffected, compared with the wild-type.
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Analysis Tools