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Tg(KRT14-Dkk4)1Dsch
Transgene Detail
Summary
Symbol: Tg(KRT14-Dkk4)1Dsch
Name: transgene insertion 1, David Schlessinger
MGI ID: MGI:5824108
Synonyms: K14-Dkk4TG
Transgene: Tg(KRT14-Dkk4)1Dsch  Location: unknown  
Alliance: Tg(KRT14-Dkk4)1Dsch page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(KRT14-Dkk4)1Dsch expresses 1 gene
 
Mutation detailsThis transgene shows skin-specific expression of mouse Dkk4 under KRT14 promoter control. Sharply elevated expression in the back skin of transgenic mice from E14.5 was detectable by Q-PCR assays, and Western blotting confirmed the increased expression of Dkk4 protein in the soluble fraction of E16.5 transgenic skin extract. No line information was given. (J:238689)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:238689 Cui CY, et al., Dkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair. PLoS One. 2010 Apr 01;5(4):e10009
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory