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Tg(Mpz)140.12Wra
Transgene Detail
Summary
Symbol: Tg(Mpz)140.12Wra
Name: transgene insertion 140.12, Lawrence Wrabetz
MGI ID: MGI:5824071
Synonyms: P0ct-myc, Tg(Mpz3Myc)1Wra
Transgene: Tg(Mpz)140.12Wra  Location: unknown  
Alliance: Tg(Mpz)140.12Wra page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Mpz)140.12Wra expresses 1 gene
 
Mutation detailsThe entire mouse Mpz gene (including 6 kb of promoter sequences, all exons and introns, and the natural polyadenylation site) was used as the transgene. A myc tag was inserted at the end of the coding region. Twelve lines were generated, and line 140.12 was kept for further analysis. (J:171510)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:171510 Fratta P, et al., P0S63del impedes the arrival of wild-type P0 glycoprotein to myelin in CMT1B mice. Hum Mol Genet. 2011 Jun 1;20(11):2081-90
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory