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Gene Expression Data
Assay Details
Assay
Reference: J:93072 Cupit LD, et al., Distinct PAR/IQGAP expression patterns during murine development: implications for thrombin-associated cytoskeletal reorganization. Mamm Genome. 2004 Aug;15(8):618-29
Assay type: RNA in situ
MGI Accession ID: MGI:5823065
Gene symbol: Iqgap2
Gene name: IQ motif containing GTPase activating protein 2
Probe: IMAGE clone 3810391
Probe preparation: Antisense labelled with fluorescein RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4 E9: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS15: surface ectoderm Present Signal was present in skin.
TS15: heart Trace
TS15: central nervous system Absent
TS15: lung Absent
TS15: muscle tissue Absent
TS15: hepatic primordium Absent Signal was absent in liver.
TS15: gut Absent Signal was absent in intestine.
TS15: embryo mesenchyme Absent Signal was absent in cartilage.

Specimen 4 E10: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: surface ectoderm Present Signal was present in skin.
TS16: heart Present
TS16: central nervous system Absent
TS16: liver Absent
TS16: lung Absent
TS16: muscle tissue Absent
TS16: gut Absent Signal was absent in intestine.
TS16: embryo mesenchyme Absent Signal was absent in cartilage.

Specimen 4 E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: surface ectoderm Present Signal was present in skin.
TS18: heart Present At E11, expression in the heart increased.
TS18: muscle tissue Present
TS18: central nervous system Trace
TS18: intestine Trace
TS18: lung Trace
TS18: liver Absent
TS18: embryo mesenchyme Present Signal was present in cartilage.

Specimen 4 E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: cartilage Present
TS20: central nervous system Present
TS20: heart Present
TS20: muscle tissue Present
TS20: skin Present
TS20: intestine Absent
TS20: liver Absent
TS20: lung Absent

Specimen 4 E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: cartilage Present Expression significantly increased at E13.
TS21: central nervous system Present Expression significantly increased at E13.
TS21: heart Present
TS21: muscle tissue Present
TS21: skin Present
TS21: intestine Absent
TS21: lung Absent
TS21: liver Trace

Specimen 4 E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cartilage Present Expression significantly increased at E14.
TS22: central nervous system Present Expression significantly increased at E14.
TS22: heart Present
TS22: muscle tissue Present
TS22: skin Present
TS22: intestine Absent
TS22: liver Absent
TS22: lung Absent

Specimen 4 E15: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cartilage Present Expression decreased at E15.
TS23: central nervous system Present Expression decreased at E15.
TS23: muscle tissue Present Expression increased markedly in muscle.
TS23: heart Present
TS23: skin Present
TS23: intestine Absent
TS23: liver Absent
TS23: lung Absent

Specimen 4 E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: skin Strong
TS24: cartilage Present
TS24: central nervous system Present
TS24: heart Present
TS24: muscle tissue Present
TS24: intestine Absent
TS24: liver Absent
TS24: lung Absent

Specimen 5A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: epidermis Strong Regionally restricted 5A IQGAP2 Intense expression was detected in the stratum spongiosum.
TS23: brain gray matter Present Regionally restricted 5A IQGAP2 Expression was detected in the deep areas of paraventricular gray matter.
TS23: cartilage Strong Regionally restricted 5A IQGAP2 Heavy expression was noted in proliferating centers of maturing cartilage.

Specimen 5B Skin: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: epidermis Strong Regionally restricted 5B IQGAP2 Skin Intense expression was detected in the stratum spongiosum.

Specimen 5B Cartilage: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: vertebral cartilage condensation Strong Regionally restricted 5B IQGAP2 Cartilage Heavy expression was noted in proliferating centers of maturing cartilage.

Specimen 5B Brain: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: brain gray matter Present Regionally restricted 5B IQGAP2 Brain Expression was detected in the deep areas of paraventricular gray matter.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory