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Gene Expression Data
Assay Details
Assay
Reference: J:15713 David G, et al., Spatial and temporal changes in the expression of fibroglycan (syndecan-2) during mouse embryonic development. Development. 1993 Nov;119(3):841-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5822807
Gene symbol: Sdc2
Gene name: syndecan 2
Antibody: anti-fibroglycan 10H4
Detection system: horseradish peroxidase
Results
Specimen 7A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: lung mesenchyme Strong Regionally restricted 7A Basement membrane-like expression at interface between first epithelial branches and the mesenchyme.
TS20: lung epithelium Absent 7A

Specimen 7B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: lung mesenchyme Strong Regionally restricted 7B Expression completely surrounds the mesenchymal cells in close contact with the stalks of the epithelial branches. At the tips of the branches, basement membrane-like expression.
TS21: lung epithelium Absent 7B

Specimen 7C/D: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: lung mesenchyme Strong Regionally restricted 7C , 7D Expression in a layer of mesenchymal cells surrounding the primary and secondary branches. No expression in mesenchymal cells near the tips and distant mesenchymal cell.
TS25: lung epithelium Absent 7D , 7C

Specimen 8A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: sclerotome Weak 8A Authors report a slight accentuation of the expression in more anterior somites.
TS20: dermatome Weak 8A
TS20: myotome Absent 8A

Specimen 8B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: sclerotome Absent 8B
TS18: limb mesenchyme Weak 8B

Specimen 8C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: vertebral pre-cartilage condensation Present 8C Expression in aggregated mesenchyme of vertebral primordia.

Specimen 8D: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: digit mesenchyme Present Regionally restricted 8D Strong expression in perichondrial, periosteal, periarticular, tendinous and dermal tissues of the digits.

Specimen 8E: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: intervertebral disc Strong 8E Strong staining of the intervertebral fissure.
TS25: vertebral cartilage condensation Weak 8E Progressively decreasing expression in hypertrophic cartilage of vertebral bodies.

Specimen 8F: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: foot mesenchyme Present Regionally restricted 8F Strong expression in perichondrial, periosteal, periarticular, tendinous and dermal tissues of the foot.

Specimen 9A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: jaw primordium mesenchyme Present Regionally restricted 9A In the jaw mesenchyme, expression at interface with ectoderm and around the invaginating buds.
TS20: vibrissa mesenchyme Present 9A In the jaw mesenchyme, expression at interface with ectoderm and around the invaginating buds.

Specimen 9B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: dental sac Strong 9B
TS23: mandible Present Regionally restricted 9B Expression hardly detectable on scattered mesenchymal cells; became pronounced once cells aggreagated in osteogenic core; persisted in differentiating osteoblasts.

Specimen 9C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: jaw mesenchyme Present Regionally restricted 9C Expression at interface with the ectoderm and around the invaginating buds.
TS23: vibrissa Present Regionally restricted 9C Expression at interface with the ectoderm and around the invaginating buds.

Specimen 9D: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: adrenal gland Present Regionally restricted 9D Expression in a group of medullar cells, but undetectable in the adrenal cortex.

Specimen 9E: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: vibrissa Present Regionally restricted 9E Expression particularly pronounced in mesenchyme surrounding vibrissa. Expression at interface between mesenchyme and epitheium, bot not in embryonic epithelium.

Specimen 9F: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: ganglion Absent 9F Authors state expression is undetectable in neural ganglia.

Specimen 10A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: lung mesenchyme Present Regionally restricted 10A Expression in epithelial- and mesothelial-mesenchymal interfaces.

Specimen 10C: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: pancreas mesenchyme Present Regionally restricted 10C Expression in epithelial- and mesothelial-mesenchymal interfaces.

Specimen 10E: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Present Regionally restricted 10E Expression in periepithelial mesenchyme.
TS21: metanephros epithelium Absent 10E Expression in periepithelial mesenchyme.

Specimen 10G: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: stomach mesenchyme Strong Regionally restricted 10G Expression in mesenchyme, mostly on cells and structures in proximity with epithelial tissue.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory