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Gene Expression Data
Assay Details
Assay
Reference: J:69359 Van de Putte T, et al., Mice with a homozygous gene trap vector insertion in mgcRacGAP die during pre-implantation development. Mech Dev. 2001 Apr;102(1-2):33-44
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5818922
Gene symbol: Racgap1
Gene name: Rac GTPase-activating protein 1
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 2.0; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 1A
Specimen morula not shown: embryonic day 2.5; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS4: compacted morula Present
Specimen 1B: embryonic day 3.5; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present 1B
TS4: trophectoderm Present 1B
Specimen 1C: embryonic day 9.5; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS15: neural fold Present 1C
Specimen 1D: embryonic day 12.5; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS20: brain Present Regionally restricted 1D Expression levels elevated in neural epithelium of neural tube and brain vesicles.
TS20: spinal cord Present Regionally restricted 1D Expression levels elevated in neural epithelium of neural tube and brain vesicles.
TS20: heart Weak 1D
TS20: limb Weak 1D
Specimen 1J: postnatal adult; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Strong Regionally restricted 1J
Specimen 1K: postnatal adult; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Regionally restricted 1K Expression in Purkinje cell layer, extending into molecular layer.
TS28: cerebellum molecular layer Present Regionally restricted 1K Expression in Purkinje cell layer, extending into molecular layer.
TS28: cerebellum granule cell layer Absent 1K
Specimen 1L: postnatal adult; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Regionally restricted 1L Expression in Purkinje cell layer, extending into molecular layer.
TS28: cerebellum molecular layer Present Regionally restricted 1L Expression in Purkinje cell layer, extending into molecular layer.
TS28: cerebellum granule cell layer Absent 1L
Specimen adult brain not shown: postnatal adult; Racgap1Gt(pSABetageo)11Huy/Racgap1+ (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted Expression in other discrete brain regions, such as hippocampus (strongest in CA3).
TS28: hippocampus CA3 Strong In hippocampus, strongest expression in CA3.
TS28: accumbens nucleus Present Regionally restricted Relatively high levels of expression in shell of nucleus accumbens.
TS28: central amygdaloid nucleus Present
TS28: piriform cortex Present
TS28: brain white matter Present Regionally restricted Expression in habenular commissure.
TS28: cerebral cortex Present Scattered Expression in cells scattered sparcely throughout all layers of cortex.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory